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What is tizanidine? Tizanidine is a short-acting muscle relaxer. It works by blocking nerve impulses (pain sensations) that are sent to your brain. Tizanidine is used to treat spasticity by temporarily relaxing muscle tone. Tizanidine may also be used for purposes not listed in this medication guide. Warnings Tizanidine is a short-acting medication that should be taken only for daily activities that require relief from muscle spasticity. You should not take tizanidine if you are also taking fluvoxamine (Luvox) or ciprofloxacin (Cipro). Do not use tizanidine at a time when you need muscle tone for safe balance and movement during certain activities. In some situations, it may endanger your physical safety to be in a state of reduced muscle tone. Switching between tablets and capsules, or changing the way you take it with regard to eating, can cause an increase in side effects or a decrease in therapeutic effect. Follow your doctor's instructions carefully. After making any changes in how you take tizanidine, contact your doctor if you notice any change in how well the medicine works or if it causes increased side effects. The recommended starting dose of tizanidine is 2 mg every 6 to 8 hours, up to a maximum of 3 doses in 24 hours. Do not take more than 36 mg of tizanidine in a 24-hour period. Too much of this medicine can damage your liver. Cold or allergy medicine, narcotic pain medicine, sleeping pills, other muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by tizanidine. Avoid drinking alcohol. It can increase some of the side effects of this medicine. Before taking this medicine You should not use tizanidine if you are allergic to it, or if: you also take the antidepressant fluvoxamine (Luvox); or you also take the antibiotic ciprofloxacin (Cipro). To make sure tizanidine is safe for you, tell your doctor if you have ever had: liver disease; kidney disease; or low blood pressure. It is not known whether tizanidine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. How should I take tizanidine? Take tizanidine exactly as it was prescribed for you. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended. Tizanidine is usually taken up to 3 times in one day, starting at 2mg per dose. Allow 6 to 8 hours to pass between doses. Do not take more than 36 mg in a 24-hour period. Too much of this medicine can damage your liver. You may take tizanidine with or without food, but take it the same way each time. Switching between taking with food and taking it without food can make the medicine less effective or cause increased side effects. Switching between tablets and capsules may cause changes in side effects or how well the medicine works. Taking the tablets with food can increase your blood levels of tizanidine. Taking the capsules with food can decrease your blood levels of tizanidine. If you make any changes in how you take tizanidine, tell your doctor if you notice any change in side effects or in how well the medicine works. Tizanidine is a short-acting medication, and its effects will be most noticeable between 1 and 3 hours after you take it. You should take this medicine only for daily activities that require relief from muscle spasms. You will need frequent blood tests to check your liver function. If you stop using this medicine suddenly after long-term use, you may have withdrawal symptoms such as dizziness, fast heartbeats, tremors, and anxiety. Ask your doctor how to safely stop using this medicine. Store at room temperature away from moisture and heat. What happens if I miss a dose? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include weakness, drowsiness, confusion, slow heart rate, shallow breathing, feeling light-headed, or fainting. What to avoid Do not use tizanidine at a time when you need muscle tone for safe balance and movement during certain activities. In some situations, it may be dangerous for you to have reduced muscle tone. Drinking alcohol with this medicine can cause side effects. Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Tizanidine side effects Get emergency medical help if you have signs of an allergic reaction to tizanidine: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: a light-headed feeling, like you might pass out; weak or shallow breathing; confusion, hallucinations; or pain or burning when you urinate. Common tizanidine side effects may include: drowsiness, dizziness, weakness; feeling nervous; blurred vision; flu-like symptoms; dry mouth, trouble speaking; abnormal liver function tests; runny nose, sore throat; urination problems, painful urination; vomiting, constipation; or uncontrolled muscle movements. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. What other drugs will affect tizanidine? Taking tizanidine with other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. Tell your doctor about all your other medicines, especially: acyclovir; ticlopidine; zileuton; birth control pills; an antibiotic - ciprofloxacin, levofloxacin, moxifloxacin, or ofloxacin; blood pressure medicine - clonidine, guanfacine, methyldopa; heart rhythm medicine - amiodarone, mexiletine, propafenone, verapamil; or stomach acid medicine - cimetidine, famotidine. This list is not complete. Other drugs may interact with tizanidine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
What is tolterodine? Tolterodine is used in adults to treat overactive bladder with symptoms of urinary frequency, urgency, and incontinence (urine leakage). Tolterodine may also be used for purposes not listed in this medication guide. Warnings Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies. Before taking this medicine You should not use tolterodine if you are allergic to tolterodine or fesoterodine (Toviaz), or if you have: trouble emptying your bladder; a blockage in your stomach, slow digestion; or uncontrolled narrow-angle glaucoma. Tell your doctor if you have ever had: a stomach or intestinal disorder; problems with constipation; liver disease; kidney disease; myasthenia gravis; trouble emptying your bladder, or a weak stream of urine; glaucoma; or long QT syndrome (in you or a family member). Tell your doctor if you are pregnant or breastfeeding. How should I take tolterodine? Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Take with water. Take tolterodine with or without food, at the same times each day. Swallow the capsule whole and do not crush, chew, break, or open it. Store at room temperature away from moisture, heat, and light. What happens if I miss a dose? Skip the missed dose and use your next dose at the regular time. Do not use 2 doses in one day What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking tolterodine? Avoid driving or hazardous activity until you know how tolterodine will affect you. Your reactions could be impaired. Tolterodine side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using tolterodine and call your doctor at once if you have: confusion, hallucinations; severe stomach pain or constipation; or painful or difficult urination. Common side effects may include: dry mouth; dizziness; constipation; stomach pain; or headache. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Tolterodine dosing information Usual Adult Dose for Urinary Incontinence: Immediate release tablets: -Initial dose: 2 mg orally 2 times a day -Maintenance dose: 1 to 2 mg orally 2 times a day, depending on patient response and tolerability Extended release capsules: -Initial dose: 4 mg orally once a day -Maintenance dose: 2 to 4 mg orally once a day, depending on patient response and tolerability Comments: -This drug can be taken with or without food. -The extended release formulation should be swallowed whole. Use: For the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and frequency Usual Adult Dose for Urinary Frequency: Immediate release tablets: -Initial dose: 2 mg orally 2 times a day -Maintenance dose: 1 to 2 mg orally 2 times a day, depending on patient response and tolerability Extended release capsules: -Initial dose: 4 mg orally once a day -Maintenance dose: 2 to 4 mg orally once a day, depending on patient response and tolerability Comments: -This drug can be taken with or without food. -The extended release formulation should be swallowed whole. Use: For the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and frequency What other drugs will affect tolterodine? Tolterodine can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV. Tell your doctor about all your other medicines, especially: cyclosporine; or vinblastine. This list is not complete. Other drugs may affect tolterodine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
What is tolterodine? Tolterodine is used in adults to treat overactive bladder with symptoms of urinary frequency, urgency, and incontinence (urine leakage). Tolterodine may also be used for purposes not listed in this medication guide. Warnings Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies. Before taking this medicine You should not use tolterodine if you are allergic to tolterodine or fesoterodine (Toviaz), or if you have: trouble emptying your bladder; a blockage in your stomach, slow digestion; or uncontrolled narrow-angle glaucoma. Tell your doctor if you have ever had: a stomach or intestinal disorder; problems with constipation; liver disease; kidney disease; myasthenia gravis; trouble emptying your bladder, or a weak stream of urine; glaucoma; or long QT syndrome (in you or a family member). Tell your doctor if you are pregnant or breastfeeding. How should I take tolterodine? Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Take with water. Take tolterodine with or without food, at the same times each day. Swallow the capsule whole and do not crush, chew, break, or open it. Store at room temperature away from moisture, heat, and light. What happens if I miss a dose? Skip the missed dose and use your next dose at the regular time. Do not use 2 doses in one day What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking tolterodine? Avoid driving or hazardous activity until you know how tolterodine will affect you. Your reactions could be impaired. Tolterodine side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using tolterodine and call your doctor at once if you have: confusion, hallucinations; severe stomach pain or constipation; or painful or difficult urination. Common side effects may include: dry mouth; dizziness; constipation; stomach pain; or headache. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Tolterodine dosing information Usual Adult Dose for Urinary Incontinence: Immediate release tablets: -Initial dose: 2 mg orally 2 times a day -Maintenance dose: 1 to 2 mg orally 2 times a day, depending on patient response and tolerability Extended release capsules: -Initial dose: 4 mg orally once a day -Maintenance dose: 2 to 4 mg orally once a day, depending on patient response and tolerability Comments: -This drug can be taken with or without food. -The extended release formulation should be swallowed whole. Use: For the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and frequency Usual Adult Dose for Urinary Frequency: Immediate release tablets: -Initial dose: 2 mg orally 2 times a day -Maintenance dose: 1 to 2 mg orally 2 times a day, depending on patient response and tolerability Extended release capsules: -Initial dose: 4 mg orally once a day -Maintenance dose: 2 to 4 mg orally once a day, depending on patient response and tolerability Comments: -This drug can be taken with or without food. -The extended release formulation should be swallowed whole. Use: For the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and frequency What other drugs will affect tolterodine? Tolterodine can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV. Tell your doctor about all your other medicines, especially: cyclosporine; or vinblastine. This list is not complete. Other drugs may affect tolterodine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
What is topiramate? Topiramate is a seizure medicine, also called an anticonvulsant. Topiramate is used to treat certain types of seizures in adults and children who are at least 2 years old. Trokendi XR is for use in adults and children who are at least 6 years old. Some brands of topiramate are also used to prevent migraine headaches in adults and teenagers who are at least 12 years old. These medicines will only prevent migraine headaches or reduce the number of attacks, but will not treat a headache that has already begun. Topiramate may also be used for purposes not listed in this medication guide. Warnings Topiramate may cause vision problems that can be permanent if not treated quickly. Call your doctor right away if you have a sudden decrease in vision. Topiramate can increase body temperature and decrease sweating, which may lead to life-threatening dehydration. Tell your doctor if you have decreased sweating, high fever, and hot dry skin. Some people have thoughts about suicide while taking seizure medicine. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor. Before taking this medicine You should not use topiramate if you are allergic to it. Do not take Trokendi XR within 6 hours before or 6 hours after drinking alcohol. Tell your doctor if you are sick with diarrhea, or if you have ever had: glaucoma or other eye problems; metabolic acidosis (high levels of acid in your blood); kidney disease, kidney stones, or dialysis; lung disease, breathing problems; mood problems, depression, or suicidal thoughts or actions; liver disease; a growth disorder; or soft or brittle bones (osteoporosis, osteomalacia). Topiramate can increase the level of acid in your blood (metabolic acidosis). This can weaken your bones, cause kidney stones, or cause growth problems in children or harm to an unborn baby. You may need blood tests to make sure you do not have metabolic acidosis, especially if you are pregnant. Some people have thoughts about suicide while taking an anticonvulsant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms. Taking topiramate during pregnancy may increase the risk of cleft lip and/or cleft palate, a birth defect that can develop early in pregnancy even before you know you are pregnant. However, having a seizure during pregnancy could harm both the mother and the baby. Tell your doctor right away if you become pregnant. If you take topiramate during pregnancy: The benefit of preventing seizures may outweigh any risks posed by topiramate. There may be other medications that are safer to use. Do not start or stop taking topiramate without your doctor's advice. If you are not pregnant or planning to become pregnant, use effective birth control to prevent pregnancy while taking topiramate. Topiramate can make birth control pills less effective. Ask your doctor about other birth control options such as an injection, implant, skin patch, vaginal ring, condom, diaphragm, cervical cap, or contraceptive sponge. It may not be safe to breastfeed a baby while you are using this medicine. Ask your doctor about any risks. How should I take topiramate? Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Topiramate can be taken with or without food. Swallow the tablet whole and do not crush, chew, or break it. The Trokendi XR extended-release capsule must be swallowed whole. Do not break or open. Measure liquid medicine with the supplied measuring device (not a kitchen spoon). If you cannot swallow a Qudexy XR or Topamax Sprinkle Capsule whole, open it and sprinkle the medicine into a spoonful of applesauce or other soft food. Swallow the mixture right away without chewing. Do not save it for later use. Carefully follow the swallowing instructions for your medicine. Topiramate doses are sometimes based on weight in children. Your child's dose needs may change if the child gains or loses weight. Drink plenty of liquids while you are taking topiramate, to prevent kidney stones or an electrolyte imbalance. You will need frequent medical tests. If you need surgery, tell the surgeon ahead of time that you are using topiramate. Any medical care provider who treats you should know that you take seizure medication. Do not stop using topiramate suddenly, even if you feel fine. Stopping suddenly may cause increased seizures. Follow your doctor's instructions about tapering your dose. Call your doctor if your seizures get worse or you have them more often while taking topiramate. Store at cool room temperature away from moisture, light, and high heat. What happens if I miss a dose? Take the medicine as soon as you can. Do not take two doses at one time. Skip a missed Topamax dose if your next dose is due in less than 6 hours. Call your doctor if you have missed more than one dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of topiramate can be fatal. Overdose can cause drowsiness, agitation, depression, double vision, thinking problems, problems with speech or coordination, fainting, and seizure (convulsions). What should I avoid while taking topiramate? Do not drink alcohol. Dangerous side effects or increased seizures may occur. Avoid becoming overheated or dehydrated in hot weather. Topiramate can increase body temperature and decrease sweating, leading to life-threatening dehydration (especially in children). Avoid the use of a ketogenic or "ketosis" diet (high in fat, low in carbohydrates) while you are taking topiramate. Topiramate may cause blurred vision or impair your thinking or reactions. Avoid driving or operating machinery until you know how topiramate will affect you. Also avoid activities that could be dangerous if you have an unexpected seizure, such as swimming or climbing in high places. Topiramate side effects Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling). Report any new or worsening mood symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), depressed, or have thoughts about suicide or hurting yourself. Call your doctor at once if you have: a skin rash, no matter how mild; vision problems, blurred vision, eye pain or redness, sudden vision loss (can be permanent if not treated quickly); confusion, problems with thinking or memory, trouble concentrating, problems with speech; dehydration symptoms--decreased sweating, high fever, hot and dry skin; signs of a kidney stone--severe pain in your side or lower back, painful or difficult urination; signs of too much acid in your blood--irregular heartbeats, feeling tired, loss of appetite, trouble thinking, feeling short of breath; or signs of too much ammonia in your blood--vomiting, unexplained weakness, feeling like you might pass out. Common side effects may include: dizziness, drowsiness, tiredness, slow reactions; problems with speech or memory, abnormal vision; numbness or tingling in your arms and legs, decreased sensation (especially in the skin); changes in your sense of taste, feeling nervous; nausea, diarrhea, stomach pain, loss of appetite; fever, weight loss; or cold symptoms such as stuffy nose, sneezing, sore throat. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. What other drugs will affect topiramate? Using topiramate with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or depression. Tell your doctor about all your other medicines, especially: zonisamide; birth control pills; divalproex, valproic acid; or other glaucoma medications, including eye drops. This list is not complete. Other drugs may affect topiramate, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
What is topiramate? Topiramate is a seizure medicine, also called an anticonvulsant. Topiramate is used to treat certain types of seizures in adults and children who are at least 2 years old. Trokendi XR is for use in adults and children who are at least 6 years old. Some brands of topiramate are also used to prevent migraine headaches in adults and teenagers who are at least 12 years old. These medicines will only prevent migraine headaches or reduce the number of attacks, but will not treat a headache that has already begun. Topiramate may also be used for purposes not listed in this medication guide. Warnings Topiramate may cause vision problems that can be permanent if not treated quickly. Call your doctor right away if you have a sudden decrease in vision. Topiramate can increase body temperature and decrease sweating, which may lead to life-threatening dehydration. Tell your doctor if you have decreased sweating, high fever, and hot dry skin. Some people have thoughts about suicide while taking seizure medicine. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor. Before taking this medicine You should not use topiramate if you are allergic to it. Do not take Trokendi XR within 6 hours before or 6 hours after drinking alcohol. Tell your doctor if you are sick with diarrhea, or if you have ever had: glaucoma or other eye problems; metabolic acidosis (high levels of acid in your blood); kidney disease, kidney stones, or dialysis; lung disease, breathing problems; mood problems, depression, or suicidal thoughts or actions; liver disease; a growth disorder; or soft or brittle bones (osteoporosis, osteomalacia). Topiramate can increase the level of acid in your blood (metabolic acidosis). This can weaken your bones, cause kidney stones, or cause growth problems in children or harm to an unborn baby. You may need blood tests to make sure you do not have metabolic acidosis, especially if you are pregnant. Some people have thoughts about suicide while taking an anticonvulsant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms. Taking topiramate during pregnancy may increase the risk of cleft lip and/or cleft palate, a birth defect that can develop early in pregnancy even before you know you are pregnant. However, having a seizure during pregnancy could harm both the mother and the baby. Tell your doctor right away if you become pregnant. If you take topiramate during pregnancy: The benefit of preventing seizures may outweigh any risks posed by topiramate. There may be other medications that are safer to use. Do not start or stop taking topiramate without your doctor's advice. If you are not pregnant or planning to become pregnant, use effective birth control to prevent pregnancy while taking topiramate. Topiramate can make birth control pills less effective. Ask your doctor about other birth control options such as an injection, implant, skin patch, vaginal ring, condom, diaphragm, cervical cap, or contraceptive sponge. It may not be safe to breastfeed a baby while you are using this medicine. Ask your doctor about any risks. How should I take topiramate? Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Topiramate can be taken with or without food. Swallow the tablet whole and do not crush, chew, or break it. The Trokendi XR extended-release capsule must be swallowed whole. Do not break or open. Measure liquid medicine with the supplied measuring device (not a kitchen spoon). If you cannot swallow a Qudexy XR or Topamax Sprinkle Capsule whole, open it and sprinkle the medicine into a spoonful of applesauce or other soft food. Swallow the mixture right away without chewing. Do not save it for later use. Carefully follow the swallowing instructions for your medicine. Topiramate doses are sometimes based on weight in children. Your child's dose needs may change if the child gains or loses weight. Drink plenty of liquids while you are taking topiramate, to prevent kidney stones or an electrolyte imbalance. You will need frequent medical tests. If you need surgery, tell the surgeon ahead of time that you are using topiramate. Any medical care provider who treats you should know that you take seizure medication. Do not stop using topiramate suddenly, even if you feel fine. Stopping suddenly may cause increased seizures. Follow your doctor's instructions about tapering your dose. Call your doctor if your seizures get worse or you have them more often while taking topiramate. Store at cool room temperature away from moisture, light, and high heat. What happens if I miss a dose? Take the medicine as soon as you can. Do not take two doses at one time. Skip a missed Topamax dose if your next dose is due in less than 6 hours. Call your doctor if you have missed more than one dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of topiramate can be fatal. Overdose can cause drowsiness, agitation, depression, double vision, thinking problems, problems with speech or coordination, fainting, and seizure (convulsions). What should I avoid while taking topiramate? Do not drink alcohol. Dangerous side effects or increased seizures may occur. Avoid becoming overheated or dehydrated in hot weather. Topiramate can increase body temperature and decrease sweating, leading to life-threatening dehydration (especially in children). Avoid the use of a ketogenic or "ketosis" diet (high in fat, low in carbohydrates) while you are taking topiramate. Topiramate may cause blurred vision or impair your thinking or reactions. Avoid driving or operating machinery until you know how topiramate will affect you. Also avoid activities that could be dangerous if you have an unexpected seizure, such as swimming or climbing in high places. Topiramate side effects Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling). Report any new or worsening mood symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), depressed, or have thoughts about suicide or hurting yourself. Call your doctor at once if you have: a skin rash, no matter how mild; vision problems, blurred vision, eye pain or redness, sudden vision loss (can be permanent if not treated quickly); confusion, problems with thinking or memory, trouble concentrating, problems with speech; dehydration symptoms--decreased sweating, high fever, hot and dry skin; signs of a kidney stone--severe pain in your side or lower back, painful or difficult urination; signs of too much acid in your blood--irregular heartbeats, feeling tired, loss of appetite, trouble thinking, feeling short of breath; or signs of too much ammonia in your blood--vomiting, unexplained weakness, feeling like you might pass out. Common side effects may include: dizziness, drowsiness, tiredness, slow reactions; problems with speech or memory, abnormal vision; numbness or tingling in your arms and legs, decreased sensation (especially in the skin); changes in your sense of taste, feeling nervous; nausea, diarrhea, stomach pain, loss of appetite; fever, weight loss; or cold symptoms such as stuffy nose, sneezing, sore throat. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. What other drugs will affect topiramate? Using topiramate with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or depression. Tell your doctor about all your other medicines, especially: zonisamide; birth control pills; divalproex, valproic acid; or other glaucoma medications, including eye drops. This list is not complete. Other drugs may affect topiramate, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
What is tramadol? Tramadol is a pain medicine similar to an opioid and is classified as a synthetic opioid. It acts in the central nervous system (CNS) to relieve pain. Tramadol is used to treat moderate to severe pain in adults. The extended-release form of tramadol is for around-the-clock treatment of pain. This form of tramadol is not for use on an as-needed basis for pain. Warnings Seizures have been reported in patients taking tramadol. Your risk of seizures is higher if you are taking higher doses than recommended. Seizure risk is also higher in those with a seizure disorder or those taking certain antidepressants or opioid medications. Tramadol should not be used if you are suicidal or prone to addiction. You should not take tramadol if you have severe breathing problems, a blockage in your stomach or intestines, or if you have recently used alcohol, sedatives, tranquilizers, narcotic medication, or an MAO inhibitor (isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others). Tramadol can slow or stop your breathing, and may be habit-forming. MISUSE OF THIS MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription. Keep this medicine where others cannot get to it. Tramadol should not be given to a child younger than 12 years old, or anyone younger than 18 years old who recently had surgery to remove the tonsils or adenoids. Ultram ER should not be given to anyone younger than 18 years old. Taking tramadol during pregnancy may cause life-threatening withdrawal symptoms in the newborn. Fatal side effects can occur if you use this medicine with alcohol, or with other drugs that cause drowsiness or slow your breathing. Before taking this medicine You should not take tramadol if you are allergic to it, or if you have: severe asthma or breathing problems; a stomach or bowel obstruction (including paralytic ileus); if you have recently used alcohol, sedatives, tranquilizers, or narcotic medications; or if you have used an MAO inhibitor in the past 14 days (such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine). Tramadol should not be given to a child younger than 12 years old. Ultram ER should not be given to anyone younger than 18 years old. Do not give this medicine to anyone younger than 18 years old who recently had surgery to remove the tonsils or adenoids. Seizures have occurred in some people taking tramadol. Your seizure risk may be higher if you have ever had: a head injury, epilepsy or other seizure disorder; drug or alcohol addiction; or a metabolic disorder. To make sure tramadol is safe for you, tell your doctor if you have ever had: breathing problems, sleep apnea; liver or kidney disease; urination problems; problems with your gallbladder, pancreas, or thyroid; a stomach disorder; or mental illness, or suicide attempt. If you use tramadol during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks. Ask a doctor before using tramadol if you are breastfeeding. Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby. How should I take tramadol? Take tramadol exactly as prescribed by your doctor. Follow the directions on your prescription label and read all medication guides. Never use tramadol in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to take more of this medicine. Never share tramadol with another person, especially someone with a history of drug addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medicine where others cannot get to it. Selling or giving away this medicine is against the law. Stop taking all opioid medications when you start taking tramadol. Tramadol can be taken with or without food, but take it the same way each time. Swallow the capsule or tablet whole to avoid exposure to a potentially fatal overdose. Do not crush, chew, break, open, or dissolve. Measure liquid medicine with the supplied syringe or a dose-measuring device (not a kitchen spoon). Never crush or break a tramadol tablet to inhale the powder or mix it into a liquid to inject the drug into your vein. This practice has resulted in death. You may have withdrawal symptoms if you stop using tramadol suddenly. Ask your doctor before stopping the medicine. Store at room temperature away from moisture and heat. Keep track of your medicine. You should be aware if anyone is using it improperly or without a prescription. Do not keep leftover tramadol. Just one dose can cause death in someone using it accidentally or improperly. Ask your pharmacist where to locate a drug take-back disposal program. If there is no take-back program, mix the leftover medicine with cat litter or coffee grounds in a sealed plastic bag throw the bag in the trash. Dosing information Usual Adult Dose for Pain: Adults (17 years or older): 50 to 100 mg orally every 4 to 6 hours as needed for pain -For patients not requiring rapid onset of analgesic effect: Initial dose: 25 mg orally once a day; titrate in 25 mg increments every 3 days to reach a dose of 25 mg four times a day; thereafter increase by 50 mg as tolerated every 3 days Maximum dose: 400 mg per day. Usual Adult Dose for Chronic Pain: Extended-Release (ER): 18 years or older (tramadol-naive): 100 mg orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day For patients CURRENTLY receiving Immediate-Release (IR) Tramadol: Initial Dose: Calculate 24-hour IR requirement and initiate with a total daily ER dose rounded down to the next lowest 100 mg increment orally once a day Conversion from other Opioids: Discontinue all other around the clock opioid drugs prior to initiating therapy -Initial dose: 100 mg ER orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day. Usual Geriatric Dose for Pain: Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day. Usual Geriatric Dose for Chronic Pain: Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day. Usual Pediatric Dose for Pain: Tramadol is not recommended for use in pediatric patients 17 years or older: See Adult Dose. What happens if I miss a dose? Since tramadol is used for pain, you are not likely to miss a dose. Skip any missed dose if it is almost time for your next dose. Do not use two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing. Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive. Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it. What should I avoid while taking tramadol? Do not drink alcohol. Dangerous side effects or death could occur. Avoid driving or hazardous activity until you know how tramadol will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries. Tramadol side effects Get emergency medical help if you have signs of an allergic reaction to tramadol (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling). Tramadol can slow or stop your breathing, and death may occur. A person caring for you should give naloxone and/or seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up. Call your doctor at once if you have: noisy breathing, sighing, shallow breathing, breathing that stops during sleep; a slow heart rate or weak pulse; a light-headed feeling, like you might pass out; seizure (convulsions); or low cortisol levels - nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness. Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea. Serious breathing problems may be more likely in older adults and people who are debilitated or have wasting syndrome or chronic breathing disorders. Common tramadol side effects may include: constipation, nausea, vomiting, stomach pain; dizziness, drowsiness, tiredness; headache; or itching. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. What other drugs will affect tramadol? You may have breathing problems or withdrawal symptoms if you start or stop taking certain other medicines. Tell your doctor if you also use an antibiotic, antifungal medication, heart or blood pressure medication, seizure medication, or medicine to treat HIV or hepatitis C. Many other drugs can be dangerous when used with tramadol. Tell your doctor if you also use: medicine for allergies, asthma, blood pressure, motion sickness, irritable bowel, or overactive bladder; other opioid medicines; a benzodiazepine sedative like Valium, Klonopin, or Xanax; sleep medicine, muscle relaxers, or other drugs that make you drowsy; or drugs that affect serotonin, such as antidepressants, stimulants, or medicine for migraines or Parkinson's disease. This list is not complete. Other drugs may interact with tramadol, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Many other drugs can be dangerous when used with tramadol. Tell your doctor if you also use: medicine for allergies, asthma, blood pressure, motion sickness, irritable bowel, or overactive bladder; other opioid medicines; a benzodiazepine sedative like Valium, Klonopin, or Xanax; sleep medicine, muscle relaxers, or other drugs that make you drowsy; drugs that affect serotonin, such as antidepressants, stimulants, or medicine for migraines or Parkinson's disease. drugs that affect serotonin levels in your body - a stimulant, or medicine for depression, Parkinson's disease, migraine headaches, serious infections, or nausea and vomiting. This list is not complete. Many other drugs may affect tramadol. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
What is tramadol? Tramadol is a pain medicine similar to an opioid and is classified as a synthetic opioid. It acts in the central nervous system (CNS) to relieve pain. Tramadol is used to treat moderate to severe pain in adults. The extended-release form of tramadol is for around-the-clock treatment of pain. This form of tramadol is not for use on an as-needed basis for pain. Warnings Seizures have been reported in patients taking tramadol. Your risk of seizures is higher if you are taking higher doses than recommended. Seizure risk is also higher in those with a seizure disorder or those taking certain antidepressants or opioid medications. Tramadol should not be used if you are suicidal or prone to addiction. You should not take tramadol if you have severe breathing problems, a blockage in your stomach or intestines, or if you have recently used alcohol, sedatives, tranquilizers, narcotic medication, or an MAO inhibitor (isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others). Tramadol can slow or stop your breathing, and may be habit-forming. MISUSE OF THIS MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription. Keep this medicine where others cannot get to it. Tramadol should not be given to a child younger than 12 years old, or anyone younger than 18 years old who recently had surgery to remove the tonsils or adenoids. Ultram ER should not be given to anyone younger than 18 years old. Taking tramadol during pregnancy may cause life-threatening withdrawal symptoms in the newborn. Fatal side effects can occur if you use this medicine with alcohol, or with other drugs that cause drowsiness or slow your breathing. Before taking this medicine You should not take tramadol if you are allergic to it, or if you have: severe asthma or breathing problems; a stomach or bowel obstruction (including paralytic ileus); if you have recently used alcohol, sedatives, tranquilizers, or narcotic medications; or if you have used an MAO inhibitor in the past 14 days (such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine). Tramadol should not be given to a child younger than 12 years old. Ultram ER should not be given to anyone younger than 18 years old. Do not give this medicine to anyone younger than 18 years old who recently had surgery to remove the tonsils or adenoids. Seizures have occurred in some people taking tramadol. Your seizure risk may be higher if you have ever had: a head injury, epilepsy or other seizure disorder; drug or alcohol addiction; or a metabolic disorder. To make sure tramadol is safe for you, tell your doctor if you have ever had: breathing problems, sleep apnea; liver or kidney disease; urination problems; problems with your gallbladder, pancreas, or thyroid; a stomach disorder; or mental illness, or suicide attempt. If you use tramadol during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks. Ask a doctor before using tramadol if you are breastfeeding. Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby. How should I take tramadol? Take tramadol exactly as prescribed by your doctor. Follow the directions on your prescription label and read all medication guides. Never use tramadol in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to take more of this medicine. Never share tramadol with another person, especially someone with a history of drug addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medicine where others cannot get to it. Selling or giving away this medicine is against the law. Stop taking all opioid medications when you start taking tramadol. Tramadol can be taken with or without food, but take it the same way each time. Swallow the capsule or tablet whole to avoid exposure to a potentially fatal overdose. Do not crush, chew, break, open, or dissolve. Measure liquid medicine with the supplied syringe or a dose-measuring device (not a kitchen spoon). Never crush or break a tramadol tablet to inhale the powder or mix it into a liquid to inject the drug into your vein. This practice has resulted in death. You may have withdrawal symptoms if you stop using tramadol suddenly. Ask your doctor before stopping the medicine. Store at room temperature away from moisture and heat. Keep track of your medicine. You should be aware if anyone is using it improperly or without a prescription. Do not keep leftover tramadol. Just one dose can cause death in someone using it accidentally or improperly. Ask your pharmacist where to locate a drug take-back disposal program. If there is no take-back program, mix the leftover medicine with cat litter or coffee grounds in a sealed plastic bag throw the bag in the trash. Dosing information Usual Adult Dose for Pain: Adults (17 years or older): 50 to 100 mg orally every 4 to 6 hours as needed for pain -For patients not requiring rapid onset of analgesic effect: Initial dose: 25 mg orally once a day; titrate in 25 mg increments every 3 days to reach a dose of 25 mg four times a day; thereafter increase by 50 mg as tolerated every 3 days Maximum dose: 400 mg per day. Usual Adult Dose for Chronic Pain: Extended-Release (ER): 18 years or older (tramadol-naive): 100 mg orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day For patients CURRENTLY receiving Immediate-Release (IR) Tramadol: Initial Dose: Calculate 24-hour IR requirement and initiate with a total daily ER dose rounded down to the next lowest 100 mg increment orally once a day Conversion from other Opioids: Discontinue all other around the clock opioid drugs prior to initiating therapy -Initial dose: 100 mg ER orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day. Usual Geriatric Dose for Pain: Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day. Usual Geriatric Dose for Chronic Pain: Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day. Usual Pediatric Dose for Pain: Tramadol is not recommended for use in pediatric patients 17 years or older: See Adult Dose. What happens if I miss a dose? Since tramadol is used for pain, you are not likely to miss a dose. Skip any missed dose if it is almost time for your next dose. Do not use two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing. Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive. Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it. What should I avoid while taking tramadol? Do not drink alcohol. Dangerous side effects or death could occur. Avoid driving or hazardous activity until you know how tramadol will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries. Tramadol side effects Get emergency medical help if you have signs of an allergic reaction to tramadol (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling). Tramadol can slow or stop your breathing, and death may occur. A person caring for you should give naloxone and/or seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up. Call your doctor at once if you have: noisy breathing, sighing, shallow breathing, breathing that stops during sleep; a slow heart rate or weak pulse; a light-headed feeling, like you might pass out; seizure (convulsions); or low cortisol levels - nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness. Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea. Serious breathing problems may be more likely in older adults and people who are debilitated or have wasting syndrome or chronic breathing disorders. Common tramadol side effects may include: constipation, nausea, vomiting, stomach pain; dizziness, drowsiness, tiredness; headache; or itching. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. What other drugs will affect tramadol? You may have breathing problems or withdrawal symptoms if you start or stop taking certain other medicines. Tell your doctor if you also use an antibiotic, antifungal medication, heart or blood pressure medication, seizure medication, or medicine to treat HIV or hepatitis C. Many other drugs can be dangerous when used with tramadol. Tell your doctor if you also use: medicine for allergies, asthma, blood pressure, motion sickness, irritable bowel, or overactive bladder; other opioid medicines; a benzodiazepine sedative like Valium, Klonopin, or Xanax; sleep medicine, muscle relaxers, or other drugs that make you drowsy; or drugs that affect serotonin, such as antidepressants, stimulants, or medicine for migraines or Parkinson's disease. This list is not complete. Other drugs may interact with tramadol, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Many other drugs can be dangerous when used with tramadol. Tell your doctor if you also use: medicine for allergies, asthma, blood pressure, motion sickness, irritable bowel, or overactive bladder; other opioid medicines; a benzodiazepine sedative like Valium, Klonopin, or Xanax; sleep medicine, muscle relaxers, or other drugs that make you drowsy; drugs that affect serotonin, such as antidepressants, stimulants, or medicine for migraines or Parkinson's disease. drugs that affect serotonin levels in your body - a stimulant, or medicine for depression, Parkinson's disease, migraine headaches, serious infections, or nausea and vomiting. This list is not complete. Many other drugs may affect tramadol. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
What is acetaminophen and tramadol? Acetaminophen and tramadol is a combination medicine used to treat moderate to severe pain. Acetaminophen and tramadol contains an opioid-like medicine, and may be habit-forming. Acetaminophen and tramadol may also be used for purposes not listed in this medication guide. Warnings MISUSE OF acetaminophen and tramadol CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medicine where others cannot get to it. Do not give this medicine to anyone younger than 12 years old, or anyone under 18 who recently had surgery to remove the tonsils or adenoids. Taking this medicine during pregnancy may cause life-threatening withdrawal symptoms in the newborn. Fatal side effects can occur if you use this medicine with alcohol, or with other drugs that cause drowsiness or slow your breathing. Before taking this medicine You should not use this medicine if you are allergic to acetaminophen (Tylenol) or tramadol (Ultram), or if you have: severe asthma or breathing problems; a blockage in your stomach or intestines; or if you have used an MAO inhibitor (such as isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, tranylcypromine) in the past 14 days. Acetaminophen and tramadol is not approved for use by anyone younger than 12 years old. Do not give this medicine to anyone younger than 18 years old who recently had surgery to remove the tonsils or adenoids. Seizures have occurred in some people taking tramadol. Your risk of a seizure may be higher if you have ever had: alcoholism or drug addiction; breathing problems, sleep apnea; a metabolic disorder; a head injury, brain tumor, or seizures; or if you have recently used sedatives, tranquilizers, or narcotic medications. Tell your doctor if you have ever had: liver disease, or if you drink alcohol; kidney disease, urination problems; problems with your pancreas, gallbladder, or thyroid; or depression, mental illness, or a suicide attempt. If you use this medicine during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks. Ask a doctor before using this medicine if you are breastfeeding. Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby. How should I take acetaminophen and tramadol? Follow the directions on your prescription label and read all medication guides. Never use acetaminophen and tramadol in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to take more of this medicine. Never share acetaminophen and tramadol with another person, especially someone with a history of drug addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medicine where others cannot get to it. Selling or giving away this medicine is against the law. The maximum amount of acetaminophen and tramadol is 2 tablets per dose, or 8 tablets per day. Do not take this medicine for longer than 5 days in a row. You may take this medicine with or without food, but take it the same way each time. You should not stop using this medicine suddenly after long-term use. Follow your doctor's instructions about tapering your dose. Store at room temperature away from moisture and heat. Keep your medicine in a place where no one can use it improperly. Do not keep leftover medication. Just one dose can cause death in someone using this medicine accidentally or improperly. Ask your pharmacist where to locate a drug take-back disposal program. If there is no take-back program, mix the leftover medicine with cat litter or coffee grounds in a sealed plastic bag throw the bag in the trash. What happens if I miss a dose? Since this medicine is used for pain, you are not likely to miss a dose. Skip any missed dose if it's almost time for your next dose. Do not use two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or person using acetaminophen and tramadol without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing. Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive. Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it. What should I avoid while taking acetaminophen and tramadol? Do not drink alcohol. Dangerous side effects or death could occur. Avoid driving or operating machinery until you know how this medicine will affect you. Dizziness or severe drowsiness can cause falls or other accidents. Ask a doctor or pharmacist before using any other medicine that may contain acetaminophen (sometimes abbreviated as APAP). Taking certain medications together can lead to a fatal overdose. Acetaminophen and tramadol side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. In rare cases, acetaminophen may cause a severe skin reaction that can be fatal. This could occur even if you have taken acetaminophen in the past and had no reaction. Stop taking acetaminophen and tramadol and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling. This medicine can slow or stop your breathing, and death may occur. A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up. Stop using this medicine and call your doctor at once if you have: noisy breathing, sighing, shallow breathing, breathing that stops during sleep; a slow heart rate or weak pulse; a light-headed feeling, like you might pass out; seizure (convulsions); chest pain; liver problems--upper stomach pain, loss of appetite, dark urine, jaundice (yellowing of the skin or eyes); low cortisol levels-- nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness; or high levels of serotonin in the body--agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, diarrhea. Serious breathing problems may be more likely in older adults and in those who are debilitated or have wasting syndrome or chronic breathing disorders. Common side effects may include: dizziness, drowsiness; stomach pain, nausea, loss of appetite, diarrhea, constipation; or sweating. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Acetaminophen / tramadol side effects (more detail) Acetaminophen and tramadol dosing information Usual Adult Dose for Pain: Usual dose: 2 tablets orally every 4 to 6 hours as needed for pain Maximum dose: 8 tablets per day Maximum duration: 5 days Comments: -Each tablet contains Tramadol 37.5 mg and Acetaminophen 325 mg. Maximum daily doses are Tramadol: 300 mg per day and Acetaminophen 2600 mg per day. -Use of more than 1 product at time containing acetaminophen is not recommended. -Due to the risks of addiction, abuse, and misuse, this drug is reserved for patients who have not been or are not expected to tolerate non-opioid pain medications or who have not obtained or are not expected to obtain analgesia with other pain management treatments. Use: For the short-term (use should be limited to 5 days or less) management of acute pain, severe enough to require an opioid analgesic and for whom alternative treatments are inadequate. Detailed Acetaminophen / tramadol dosage information What other drugs will affect acetaminophen and tramadol? You may have a fatal acetaminophen and tramadol overdose if you start or stop using certain other medicines. Tell your doctor about all your medications. Many other drugs can be dangerous when used with acetaminophen and tramadol. Tell your doctor if you also use: medicine for allergies, asthma, blood pressure, motion sickness, irritable bowel, or overactive bladder; opioid medicines; a benzodiazepine sedative like Valium, Klonopin, or Xanax; sleep medicine, muscle relaxers, or other drugs that make you drowsy; or drugs that affect serotonin, such as antidepressants, stimulants, or medicine for migraines or Parkinson's disease. This list is not complete. Many drugs may affect acetaminophen and tramadol, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.
What is trandolapril? Trandolapril is an ACE inhibitor. ACE stands for angiotensin converting enzyme. Trandolapril is used to treat high blood pressure (hypertension), and to improve survival after a heart attack. Trandolapril may also be used for purposes not listed in this medication guide. Warnings Do not use if you are pregnant, and tell your doctor right away if you become pregnant. If you have diabetes, do not use trandolapril together with any medication that contains aliskiren (a blood pressure medicine). Do not take trandolapril within 36 hours before or after taking medicine that contains sacubitril (such as Entresto). Before taking this medicine You should not use trandolapril if you are allergic to it, or if you: have a history of angioedema; recently took a heart medicine called sacubitril; or are allergic to any other ACE inhibitor, such as benazepril, captopril, enalapril, fosinopril, lisinopril, moexipril, perindopril, quinapril, or ramipril. Do not take trandolapril within 36 hours before or after taking medicine that contains sacubitril (such as Entresto). If you have diabetes, do not use trandolapril together with any medication that contains aliskiren (a blood pressure medicine). You may also need to avoid taking trandolapril with aliskiren if you have kidney disease. Tell your doctor if you have ever had: kidney disease (or if you are on dialysis); liver disease; heart disease or congestive heart failure; diabetes; or if you are on a low-salt diet. Do not use if you are pregnant, and tell your doctor right away if you become pregnant. Trandolapril can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. You should not breastfeed while using trandolapril. How should I take trandolapril? Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Trandolapril can be taken with or without food. Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking trandolapril. This can lead to very low blood pressure, a serious electrolyte imbalance, or kidney failure. Your blood pressure will need to be checked often. Your kidney function and electrolytes may also need to be checked. If you need surgery, tell the surgeon ahead of time that you are using trandolapril. If you have high blood pressure, keep using this medicine even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life. Store at room temperature away from moisture and heat. Detailed Trandolapril dosage information What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking trandolapril? Do not use potassium supplements or salt substitutes, unless your doctor has told you to. Trandolapril side effects Get emergency medical help if you have signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat. You may be more likely to have an allergic reaction if you are African-American. Call your doctor at once if you have: a light-headed feeling, like you might pass out; upper stomach pain, and jaundice (yellowing of the skin or eyes); chest pain, pounding heartbeats or fluttering in your chest; high potassium level--nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement; kidney problems--little or no urination, swelling in your feet or ankles, feeling tired or short of breath; low white blood cell counts--fever, chills, feeling light-headed, mouth sores, skin sores, sore throat, cough, trouble breathing; or lung problems--anxiety, sweating, pale skin, severe shortness of breath, wheezing, gasping for breath, cough with foamy mucus. Common side effects may include: cough; dizziness; or diarrhea. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Trandolapril side effects (more detail) What other drugs will affect trandolapril? Tell your doctor about all your current medicines and any you start or stop using, especially: a diuretic or "water pill"; gold injections to treat arthritis; insulin or oral diabetes medicine; lithium; or NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others. This list is not complete. Other drugs may affect trandolapril, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here
What is trazodone? Trazodone is an antidepressant that belongs to a group of drugs called serotonin receptor antagonists and reuptake inhibitors (SARIs). While trazodone is not a true member of the selective serotonin reuptake inhibitors (SSRIs) class of antidepressants, it does still share many properties of the SSRIs. Trazodone is used to treat major depressive disorder. It may help to improve your mood, appetite, and energy level as well as decrease anxiety and insomnia related to depression. Trazodone works by helping to restore the balance of a certain natural chemical (serotonin) in the brain. Warnings You should not use trazodone if you are allergic to it, or if you are being treated with methylene blue injection. Do not use this medicine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, tranylcypromine and others. Some young people have thoughts about suicide when first taking an antidepressant. Your doctor will need to check your progress at regular visits while you are using trazodone. Your family or other caregivers should also be alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself. Do not give this medicine to anyone younger than 18 years old without the advice of a doctor. Trazodone is not approved for use in children. Before taking this medicine You should not use trazodone if you are allergic to it. Do not use this medicine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine, and others. After you stop taking trazodone, you must wait at least 14 days before you start taking an MAOI. Tell your doctor if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. An interaction with trazodone could cause a serious condition called serotonin syndrome. To make sure this medicine is safe for you, tell your doctor if you have ever had: liver or kidney disease; heart disease, or a recent heart attack; a bleeding or blood clotting disorder; seizures or epilepsy; narrow-angle glaucoma; long QT syndrome; drug addiction or suicidal thoughts; or bipolar disorder (manic depression). Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms. Taking trazodone during pregnancy could harm the baby, but stopping the medicine may not be safe for you. Do not start or stop this medicine without asking your doctor. If you are pregnant, your name may be listed on a pregnancy registry to track the effects of trazodone on the baby. It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk. Trazodone is not approved for use by anyone younger than 18 years old. How should I take trazodone? Take trazodone exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Take trazodone after a meal or a snack. It may take up to 2 weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve. You should not stop using this medicine suddenly, or you could have unpleasant symptoms (such as dizziness, vomiting, agitation, sweating, confusion, numbness, tingling, or electric shock feelings). Ask your doctor how to safely stop using this medicine. Store at room temperature away from moisture, heat, and light. Dosing information Usual Adult Dose for Depression: Initial dose: 150 mg orally per day in divided doses; this may be increased by 50 mg orally per day every 3 to 4 days Maximum dose: -Inpatients: 600 mg/day -Outpatients: 400 mg/day Comments: -Patients should be screened for a personal/family history of bipolar disorder, mania, or hypomania prior to initiating treatment. -Patients should be monitored for withdrawal symptoms when discontinuing therapy. -After an adequate response has been reached, dosage may be gradually reduced depending on therapeutic response. -If drowsiness develops, a major portion of the daily dose may be administered at bedtime or a reduction of dosage may be necessary. -This drug should be taken shortly after a meal or light snack. Use: Treatment of major depressive disorder (MDD) What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal when trazodone is taken with alcohol, barbiturates such as phenobarbital, or sedatives such as diazepam (Valium). Overdose symptoms may include extreme drowsiness, vomiting, penis erection that is painful or prolonged, fast or pounding heartbeat, seizure (black-out or convulsions), or breathing that slows or stops. What to avoid Do not drink alcohol. Dangerous side effects or death could occur. Ask your doctor before taking a nonsteroidal anti-inflammatory drug (NSAID) such as aspirin, ibuprofen, naproxen, Advil, Aleve, Motrin, and others. Using an NSAID with trazodone may cause you to bruise or bleed easily. Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Trazodone side effects Get emergency medical help if you have signs of an allergic reaction to trazodone: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking trazodone and call your doctor at once if you have a penis erection that is painful or lasts 6 hours or longer. This is a medical emergency and could lead to a serious condition that must be corrected with surgery. Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself. Call your doctor at once if you have: fast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out); slow heartbeats; unusual thoughts or behavior; easy bruising, unusual bleeding; or low levels of sodium in the body - headache, confusion, slurred speech, severe weakness, vomiting, loss of coordination, feeling unsteady. Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea. Common trazodone side effects may include: drowsiness, dizziness, tiredness; swelling; weight loss; blurred vision; diarrhea, constipation; or stuffy nose. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. What other drugs will affect trazodone? Using trazodone with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. Tell your doctor about all your current medicines. Many drugs can interact with trazodone, especially: any other antidepressants; phenytoin; St. John's wort; tramadol; a diuretic or "water pill"; medicine to treat anxiety, mood disorders, or mental illness such as schizophrenia; a blood thinner - warfarin, Coumadin, Jantoven; or migraine headache medicine - sumatriptan, Imitrex, Maxalt, Treximet, and others. This list is not complete and many other drugs may interact with trazodone. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
What is tretinoin topical? Tretinoin is a form of vitamin A that helps the skin renew itself. Tretinoin topical (for the skin) is used to treat acne, to smooth rough facial skin, and to reduce the appearance of fine wrinkles and mottled skin discoloration. Tretinoin topical may also be used for purposes not listed in this medication guide. Warnings Avoid getting this medication in your eyes, mouth, vagina, or in the creases of your nose. Before taking this medicine You should not use tretinoin topical if you are allergic to it. Do not give tretinoin topical to a child without medical advice. Some brands of tretinoin topical are not approved for use in anyone under 18. Tell your doctor if you have ever had: eczema; or an allergy to fish (the gel may contain ingredients derived from fish). It is not known whether tretinoin topical will harm an unborn baby. Tell your doctor if you are pregnant. It may not be safe to breast-feed a baby while you are using this medicine. Ask your doctor about any risks. How should I use tretinoin topical? Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Using more medicine or applying it more often than prescribed will not make it work any faster, and may increase side effects. Do not take by mouth. Topical medicine is for use only on the skin. Do not use on sunburned skin, or skin affected by eczema. Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions. Wash your hands before and after applying tretinoin topical. Before applying, clean and dry the skin area to be treated. Applying tretinoin topical to wet skin may cause skin irritation. Do not wash the treated area or apply other skin products for at least 1 hour after applying tretinoin topical. Tretinoin topical should be used as part of a complete skin care program that includes avoiding sunlight and using an effective sunscreen and protective clothing. It may take up to several weeks before your skin improves. Keep using the medication as directed and tell your doctor if your symptoms do not improve. If you are using tretinoin topical to treat acne, your condition may get slightly worse for a short time. Call your doctor if skin irritation becomes severe or if your acne does not improve within 8 to 12 weeks. Use this medicine for the full prescribed length of time, even if you think it is not working. Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use. Tretinoin topical gel is flammable. Do not use near high heat or open flame. Do not smoke until the gel has completely dried on your skin. What happens if I miss a dose? Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while using tretinoin topical? Avoid exposure to sunlight or tanning beds. Tretinoin topical can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 15 or higher) when you are outdoors, even on a cloudy day. Avoid getting this medication in your eyes, mouth, vagina, or in the creases of your nose. Avoid using skin products that can cause irritation, such as harsh soaps, shampoos, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime. Avoid using other medications on the areas you treat with tretinoin topical unless your doctor tells you to. Tretinoin topical side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: severe burning, stinging, or irritation of treated skin; severe skin dryness; or severe redness, swelling, blistering, peeling, or crusting. Your skin may be more sensitive to weather extremes such as cold and wind while using tretinoin topical. Common side effects may include: skin pain, redness, burning, itching, or irritation; sore throat; mild warmth or stinging where the medicine was applied; or changes in color of treated skin. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Tretinoin topical dosing information Usual Adult Dose for Acne: Recommended dose: Apply a thin layer to the entire affected area once a day at bedtime Comments: -Excessive amounts of the gel formulation will result in "pilling" or "caking," which prevents over-application. -Warmth and/or stinging may occur after application. -An apparent exacerbation of acne may occur during the first weeks of treatment, and should not be a reason to discontinue treatment. -Patients with and without acne reported that the gel formulation was less irritating than the cream formulation. Use: Treatment of acne vulgaris Usual Adult Dose for Dermatoheliosis: Recommended dose: Apply a pea-sized amount to the entire affected area once a day at bedtime Duration of therapy: 48 weeks (0.05% cream/emollient cream) and 52 weeks (0.02% cream) Comments: -Approximately 20 to 30 minutes prior to application, patients should wash their faces with a mild soap and pat the skin dry. -Warmth and/or stinging may occur after application. -Improvement in fine wrinkling may not be observed for up to 6 months. Use: Adjunctive agent for the mitigation of fine facial wrinkles in patients with comprehensive skin care and sunlight avoidance programs Usual Pediatric Dose for Acne: 12 years and older: -Recommended dose: Apply a thin layer to the affected area once a day at bedtime Comments: -Excessive amounts of the gel formulation will result in "pilling" or "caking," which prevents over-application. -Warmth and/or stinging may occur after application. -An apparent exacerbation of acne may occur during the first weeks of treatment, and should not be a reason to discontinue treatment. -Patients with and without acne reported that the gel formulation was less irritating than the cream formulation. Use: Treatment of acne vulgaris What other drugs will affect tretinoin topical? Do not use skin products that contain benzoyl peroxide, sulfur, resorcinol, or salicylic acid unless otherwise directed by your doctor. These products can cause severe skin irritation if used with tretinoin topical. Medicine used on the skin is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.
What is tretinoin topical? Tretinoin is a form of vitamin A that helps the skin renew itself. Tretinoin topical (for the skin) is used to treat acne, to smooth rough facial skin, and to reduce the appearance of fine wrinkles and mottled skin discoloration. Tretinoin topical may also be used for purposes not listed in this medication guide. Warnings Avoid getting this medication in your eyes, mouth, vagina, or in the creases of your nose. Before taking this medicine You should not use tretinoin topical if you are allergic to it. Do not give tretinoin topical to a child without medical advice. Some brands of tretinoin topical are not approved for use in anyone under 18. Tell your doctor if you have ever had: eczema; or an allergy to fish (the gel may contain ingredients derived from fish). It is not known whether tretinoin topical will harm an unborn baby. Tell your doctor if you are pregnant. It may not be safe to breast-feed a baby while you are using this medicine. Ask your doctor about any risks. How should I use tretinoin topical? Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Using more medicine or applying it more often than prescribed will not make it work any faster, and may increase side effects. Do not take by mouth. Topical medicine is for use only on the skin. Do not use on sunburned skin, or skin affected by eczema. Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions. Wash your hands before and after applying tretinoin topical. Before applying, clean and dry the skin area to be treated. Applying tretinoin topical to wet skin may cause skin irritation. Do not wash the treated area or apply other skin products for at least 1 hour after applying tretinoin topical. Tretinoin topical should be used as part of a complete skin care program that includes avoiding sunlight and using an effective sunscreen and protective clothing. It may take up to several weeks before your skin improves. Keep using the medication as directed and tell your doctor if your symptoms do not improve. If you are using tretinoin topical to treat acne, your condition may get slightly worse for a short time. Call your doctor if skin irritation becomes severe or if your acne does not improve within 8 to 12 weeks. Use this medicine for the full prescribed length of time, even if you think it is not working. Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use. Tretinoin topical gel is flammable. Do not use near high heat or open flame. Do not smoke until the gel has completely dried on your skin. What happens if I miss a dose? Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while using tretinoin topical? Avoid exposure to sunlight or tanning beds. Tretinoin topical can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 15 or higher) when you are outdoors, even on a cloudy day. Avoid getting this medication in your eyes, mouth, vagina, or in the creases of your nose. Avoid using skin products that can cause irritation, such as harsh soaps, shampoos, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime. Avoid using other medications on the areas you treat with tretinoin topical unless your doctor tells you to. Tretinoin topical side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: severe burning, stinging, or irritation of treated skin; severe skin dryness; or severe redness, swelling, blistering, peeling, or crusting. Your skin may be more sensitive to weather extremes such as cold and wind while using tretinoin topical. Common side effects may include: skin pain, redness, burning, itching, or irritation; sore throat; mild warmth or stinging where the medicine was applied; or changes in color of treated skin. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Tretinoin topical dosing information Usual Adult Dose for Acne: Recommended dose: Apply a thin layer to the entire affected area once a day at bedtime Comments: -Excessive amounts of the gel formulation will result in "pilling" or "caking," which prevents over-application. -Warmth and/or stinging may occur after application. -An apparent exacerbation of acne may occur during the first weeks of treatment, and should not be a reason to discontinue treatment. -Patients with and without acne reported that the gel formulation was less irritating than the cream formulation. Use: Treatment of acne vulgaris Usual Adult Dose for Dermatoheliosis: Recommended dose: Apply a pea-sized amount to the entire affected area once a day at bedtime Duration of therapy: 48 weeks (0.05% cream/emollient cream) and 52 weeks (0.02% cream) Comments: -Approximately 20 to 30 minutes prior to application, patients should wash their faces with a mild soap and pat the skin dry. -Warmth and/or stinging may occur after application. -Improvement in fine wrinkling may not be observed for up to 6 months. Use: Adjunctive agent for the mitigation of fine facial wrinkles in patients with comprehensive skin care and sunlight avoidance programs Usual Pediatric Dose for Acne: 12 years and older: -Recommended dose: Apply a thin layer to the affected area once a day at bedtime Comments: -Excessive amounts of the gel formulation will result in "pilling" or "caking," which prevents over-application. -Warmth and/or stinging may occur after application. -An apparent exacerbation of acne may occur during the first weeks of treatment, and should not be a reason to discontinue treatment. -Patients with and without acne reported that the gel formulation was less irritating than the cream formulation. Use: Treatment of acne vulgaris What other drugs will affect tretinoin topical? Do not use skin products that contain benzoyl peroxide, sulfur, resorcinol, or salicylic acid unless otherwise directed by your doctor. These products can cause severe skin irritation if used with tretinoin topical. Medicine used on the skin is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.
Warning Smoking cigarettes while using Tri-Sprintec (ethinyl estradiol and norgestimate) raises the chance of very bad heart and blood-related side effects. This chance is raised with age (mainly in women older than 35 years of age). It is also raised with the number of cigarettes smoked. It is strongly advised not to smoke. Do not use Tri-Sprintec (ethinyl estradiol and norgestimate) if you smoke and are older than 35 years of age. Uses of Tri-Sprintec: It is used to prevent pregnancy. It is used to treat pimples (acne). It may be given to you for other reasons. Talk with the doctor. What do I need to tell my doctor BEFORE I take Tri-Sprintec? If you have an allergy to ethinyl estradiol, norgestimate, or any other part of Tri-Sprintec (ethinyl estradiol and norgestimate). If you are allergic to Tri-Sprintec (ethinyl estradiol and norgestimate); any part of Tri-Sprintec (ethinyl estradiol and norgestimate); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had. If you have had any of these health problems: Blood clots, blood clotting problem, breast cancer or other cancer where hormones make it grow, diseased blood vessels in the brain or heart, disease of a heart valve with problems, heart disease, chest pain caused by angina, heart attack, stroke, high blood pressure, liver disease, liver tumor, very bad headache or migraine, or diabetes that affects blood flow. If you have had any of these health problems: Endometrial cancer, cancer of the cervix or vagina, or vaginal bleeding where the cause is not known. If you turned yellow during pregnancy or with estrogen-based or hormone contraceptive use. If you are pregnant or may be pregnant. Do not take Tri-Sprintec (ethinyl estradiol and norgestimate) if you are pregnant. If you are breast-feeding or plan to breast-feed. If you are taking ombitasvir, paritaprevir, and ritonavir (with or without dasabuvir). This is not a list of all drugs or health problems that interact with Tri-Sprintec (ethinyl estradiol and norgestimate). Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Tri-Sprintec (ethinyl estradiol and norgestimate) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. What are some things I need to know or do while I take Tri-Sprintec? Tell all of your health care providers that you take Tri-Sprintec (ethinyl estradiol and norgestimate). This includes your doctors, nurses, pharmacists, and dentists. This medicine may need to be stopped before certain types of surgery as your doctor has told you. If Tri-Sprintec (ethinyl estradiol and norgestimate) is stopped, your doctor will tell you when to start taking Tri-Sprintec (ethinyl estradiol and norgestimate) again after your surgery or procedure. This medicine may raise the chance of blood clots, a stroke, or a heart attack. Talk with the doctor. Talk with your doctor if you will need to be still for long periods of time like long trips, bedrest after surgery, or illness. Not moving for long periods may raise your chance of blood clots. If you have high blood sugar (diabetes), talk with your doctor. This medicine may raise blood sugar. Check your blood sugar as you have been told by your doctor. High blood pressure has happened with drugs like this one. Have your blood pressure checked as you have been told by your doctor. Have blood work checked as you have been told by the doctor. Talk with the doctor. This medicine may cause high cholesterol and triglyceride levels. Talk with the doctor. Be sure to have regular breast exams and gynecology check-ups. You will also need to do breast self-exams as you have been told. If you drink grapefruit juice or eat grapefruit often, talk with your doctor. This medicine may affect certain lab tests. Tell all of your health care providers and lab workers that you take Tri-Sprintec (ethinyl estradiol and norgestimate). Certain drugs, herbal products, or health problems could cause Tri-Sprintec (ethinyl estradiol and norgestimate) to not work as well. Be sure your doctor knows about all of your drugs and health problems. This medicine does not stop the spread of diseases like HIV or hepatitis that are passed through having sex. Do not have any kind of sex without using a latex or polyurethane condom. If you have questions, talk with your doctor. Do not use in children who have not had their first menstrual period. If you have any signs of pregnancy or if you have a positive pregnancy test, call your doctor right away. How is this medicine (Tri-Sprintec) best taken? Use Tri-Sprintec (ethinyl estradiol and norgestimate) as ordered by your doctor. Read all information given to you. Follow all instructions closely. Take Tri-Sprintec (ethinyl estradiol and norgestimate) at the same time of day. Take with or without food. Take with food if it causes an upset stomach. After starting Tri-Sprintec (ethinyl estradiol and norgestimate), you may need to use a non-hormone type of birth control like condoms to prevent pregnancy for some time. Follow what your doctor has told you to do about using a non-hormone type of birth control. If you also take colesevelam, take it at least 4 hours after you take Tri-Sprintec (ethinyl estradiol and norgestimate). Do not skip doses, even if you do not have sex very often. If you throw up or have diarrhea, Tri-Sprintec (ethinyl estradiol and norgestimate) may not work as well to prevent pregnancy. Use an extra form of birth control, like condoms, until you check with your doctor. If you miss 2 periods in a row, take a pregnancy test before starting a new cycle. What do I do if I miss a dose? If a dose is missed, check the package insert or call the doctor to find out what to do. If using Tri-Sprintec (ethinyl estradiol and norgestimate) to prevent pregnancy, another form of birth control may need to be used for some time to prevent pregnancy. Detailed Tri-Sprintec dosage information What are some side effects that I need to call my doctor about right away? WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes. Signs of high blood pressure like very bad headache or dizziness, passing out, or change in eyesight. Signs of gallbladder problems like pain in the upper right belly area, right shoulder area, or between the shoulder blades; yellow skin or eyes; fever with chills; bloating; or very upset stomach or throwing up. Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight. Depression or other mood changes. Feeling very tired or weak. Swelling. Not able to pass urine or change in how much urine is passed. A lump in the breast, breast pain or soreness, or nipple discharge. Vaginal itching or discharge. Eyesight changes or loss, bulging eyes, or change in how contact lenses feel. Call your doctor right away if you have signs of a blood clot like chest pain or pressure; coughing up blood; shortness of breath; swelling, warmth, numbness, change of color, or pain in a leg or arm; or trouble speaking or swallowing. Tri-Sprintec side effects (more detail) What are some other side effects of Tri-Sprintec? All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Weight gain. Headache. Upset stomach or throwing up. Gas. Feeling nervous and excitable. Stomach pain. Bloating. Feeling tired or weak. Enlarged breasts. Tender breasts. Period (menstrual) changes. These include spotting or bleeding between cycles. This medicine may cause dark patches of skin on your face. Avoid sun, sunlamps, and tanning beds. Use sunscreen and wear clothing and eyewear that protects you from the sun. These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch. If OVERDOSE is suspected: If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. How do I store and/or throw out Tri-Sprintec? Store at room temperature. Protect from light. Store in a dry place. Do not store in a bathroom. Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets. Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area. Consumer information use If your symptoms or health problems do not get better or if they become worse, call your doctor. Do not share your drugs with others and do not take anyone else's drugs. Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Tri-Sprintec (ethinyl estradiol and norgestimate), please talk with your doctor, nurse, pharmacist, or other health care provider. If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Warning Smoking cigarettes while using Tri-Sprintec (ethinyl estradiol and norgestimate) raises the chance of very bad heart and blood-related side effects. This chance is raised with age (mainly in women older than 35 years of age). It is also raised with the number of cigarettes smoked. It is strongly advised not to smoke. Do not use Tri-Sprintec (ethinyl estradiol and norgestimate) if you smoke and are older than 35 years of age. Uses of Tri-Sprintec: It is used to prevent pregnancy. It is used to treat pimples (acne). It may be given to you for other reasons. Talk with the doctor. What do I need to tell my doctor BEFORE I take Tri-Sprintec? If you have an allergy to ethinyl estradiol, norgestimate, or any other part of Tri-Sprintec (ethinyl estradiol and norgestimate). If you are allergic to Tri-Sprintec (ethinyl estradiol and norgestimate); any part of Tri-Sprintec (ethinyl estradiol and norgestimate); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had. If you have had any of these health problems: Blood clots, blood clotting problem, breast cancer or other cancer where hormones make it grow, diseased blood vessels in the brain or heart, disease of a heart valve with problems, heart disease, chest pain caused by angina, heart attack, stroke, high blood pressure, liver disease, liver tumor, very bad headache or migraine, or diabetes that affects blood flow. If you have had any of these health problems: Endometrial cancer, cancer of the cervix or vagina, or vaginal bleeding where the cause is not known. If you turned yellow during pregnancy or with estrogen-based or hormone contraceptive use. If you are pregnant or may be pregnant. Do not take Tri-Sprintec (ethinyl estradiol and norgestimate) if you are pregnant. If you are breast-feeding or plan to breast-feed. If you are taking ombitasvir, paritaprevir, and ritonavir (with or without dasabuvir). This is not a list of all drugs or health problems that interact with Tri-Sprintec (ethinyl estradiol and norgestimate). Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Tri-Sprintec (ethinyl estradiol and norgestimate) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. What are some things I need to know or do while I take Tri-Sprintec? Tell all of your health care providers that you take Tri-Sprintec (ethinyl estradiol and norgestimate). This includes your doctors, nurses, pharmacists, and dentists. This medicine may need to be stopped before certain types of surgery as your doctor has told you. If Tri-Sprintec (ethinyl estradiol and norgestimate) is stopped, your doctor will tell you when to start taking Tri-Sprintec (ethinyl estradiol and norgestimate) again after your surgery or procedure. This medicine may raise the chance of blood clots, a stroke, or a heart attack. Talk with the doctor. Talk with your doctor if you will need to be still for long periods of time like long trips, bedrest after surgery, or illness. Not moving for long periods may raise your chance of blood clots. If you have high blood sugar (diabetes), talk with your doctor. This medicine may raise blood sugar. Check your blood sugar as you have been told by your doctor. High blood pressure has happened with drugs like this one. Have your blood pressure checked as you have been told by your doctor. Have blood work checked as you have been told by the doctor. Talk with the doctor. This medicine may cause high cholesterol and triglyceride levels. Talk with the doctor. Be sure to have regular breast exams and gynecology check-ups. You will also need to do breast self-exams as you have been told. If you drink grapefruit juice or eat grapefruit often, talk with your doctor. This medicine may affect certain lab tests. Tell all of your health care providers and lab workers that you take Tri-Sprintec (ethinyl estradiol and norgestimate). Certain drugs, herbal products, or health problems could cause Tri-Sprintec (ethinyl estradiol and norgestimate) to not work as well. Be sure your doctor knows about all of your drugs and health problems. This medicine does not stop the spread of diseases like HIV or hepatitis that are passed through having sex. Do not have any kind of sex without using a latex or polyurethane condom. If you have questions, talk with your doctor. Do not use in children who have not had their first menstrual period. If you have any signs of pregnancy or if you have a positive pregnancy test, call your doctor right away. How is this medicine (Tri-Sprintec) best taken? Use Tri-Sprintec (ethinyl estradiol and norgestimate) as ordered by your doctor. Read all information given to you. Follow all instructions closely. Take Tri-Sprintec (ethinyl estradiol and norgestimate) at the same time of day. Take with or without food. Take with food if it causes an upset stomach. After starting Tri-Sprintec (ethinyl estradiol and norgestimate), you may need to use a non-hormone type of birth control like condoms to prevent pregnancy for some time. Follow what your doctor has told you to do about using a non-hormone type of birth control. If you also take colesevelam, take it at least 4 hours after you take Tri-Sprintec (ethinyl estradiol and norgestimate). Do not skip doses, even if you do not have sex very often. If you throw up or have diarrhea, Tri-Sprintec (ethinyl estradiol and norgestimate) may not work as well to prevent pregnancy. Use an extra form of birth control, like condoms, until you check with your doctor. If you miss 2 periods in a row, take a pregnancy test before starting a new cycle. What do I do if I miss a dose? If a dose is missed, check the package insert or call the doctor to find out what to do. If using Tri-Sprintec (ethinyl estradiol and norgestimate) to prevent pregnancy, another form of birth control may need to be used for some time to prevent pregnancy. Detailed Tri-Sprintec dosage information What are some side effects that I need to call my doctor about right away? WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes. Signs of high blood pressure like very bad headache or dizziness, passing out, or change in eyesight. Signs of gallbladder problems like pain in the upper right belly area, right shoulder area, or between the shoulder blades; yellow skin or eyes; fever with chills; bloating; or very upset stomach or throwing up. Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight. Depression or other mood changes. Feeling very tired or weak. Swelling. Not able to pass urine or change in how much urine is passed. A lump in the breast, breast pain or soreness, or nipple discharge. Vaginal itching or discharge. Eyesight changes or loss, bulging eyes, or change in how contact lenses feel. Call your doctor right away if you have signs of a blood clot like chest pain or pressure; coughing up blood; shortness of breath; swelling, warmth, numbness, change of color, or pain in a leg or arm; or trouble speaking or swallowing. Tri-Sprintec side effects (more detail) What are some other side effects of Tri-Sprintec? All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Weight gain. Headache. Upset stomach or throwing up. Gas. Feeling nervous and excitable. Stomach pain. Bloating. Feeling tired or weak. Enlarged breasts. Tender breasts. Period (menstrual) changes. These include spotting or bleeding between cycles. This medicine may cause dark patches of skin on your face. Avoid sun, sunlamps, and tanning beds. Use sunscreen and wear clothing and eyewear that protects you from the sun. These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch. If OVERDOSE is suspected: If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. How do I store and/or throw out Tri-Sprintec? Store at room temperature. Protect from light. Store in a dry place. Do not store in a bathroom. Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets. Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area. Consumer information use If your symptoms or health problems do not get better or if they become worse, call your doctor. Do not share your drugs with others and do not take anyone else's drugs. Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Tri-Sprintec (ethinyl estradiol and norgestimate), please talk with your doctor, nurse, pharmacist, or other health care provider. If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
What is triamcinolone? Triamcinolone belongs to a class of drugs called corticosteroids. It prevents the release of substances in the body that cause inflammation. Triamcinolone oral (taken by mouth) is used to treat many different conditions such as allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, or breathing disorders. Triamcinolone may also be used for purposes not listed in this medication guide. Warnings You should not use this medication if you are allergic to triamcinolone, or if you have a fungal infection anywhere in your body. Before taking triamcinolone, tell your doctor about all of your medical conditions, and about all other medicines you are using. There are many other disease that can be affected by steroid use, and many other medicines that can interact with steroids. Your steroid medication needs may change if you have any unusual stress such as a serious illness, fever or infection, or if you have surgery or a medical emergency. Tell your doctor about any such situation that affects you during treatment. Steroid medications such as triamcinolone can weaken your immune system, making it easier for you to get an infection or worsening an infection you already have or have recently had. Tell your doctor about any illness or infection you have had within the past several weeks. Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chicken pox or measles. These conditions can be serious or even fatal in people who are using steroid medication. Do not receive a "live" vaccine while you are taking triamcinolone. Vaccines may not work as well while you are taking a steroid. Do not stop using triamcinolone suddenly, or you could have unpleasant withdrawal symptoms. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication. Wear a medical alert tag or carry an ID card stating that you take triamcinolone. Any medical care provider who treats you should know that you take steroid medication. Before taking this medicine You should not use this medication if you are allergic to triamcinolone, or if you have a fungal infection anywhere in your body. Steroid medication can weaken your immune system, making it easier for you to get an infection. Steroids can also worsen an infection you already have, or reactivate an infection you recently had. Before taking this medication, tell your doctor about any illness or infection you have had within the past several weeks. To make sure you can safely take triamcinolone, tell your doctor if you have any of these other conditions: liver disease (such as cirrhosis); kidney disease; a thyroid disorder; diabetes; a history of malaria; tuberculosis; osteoporosis; a muscle disorder such as myasthenia gravis; glaucoma or cataracts; herpes infection of the eyes; stomach ulcers, ulcerative colitis, or diverticulitis; depression or mental illness; congestive heart failure; or high blood pressure FDA pregnancy category C. It is not known whether triamcinolone will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Triamcinolone can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Triamcinolone can affect growth in children. Talk with your doctor if you think your child is not growing at a normal rate while using triamcinolone. How should I take triamcinolone? Take triamcinolone exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results from this medication. Take triamcinolone with food to prevent stomach upset. Your steroid medication needs may change if you have unusual stress such as a serious illness, fever or infection, or if you have surgery or a medical emergency. Tell your doctor about any such situation that affects you. This medication can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you are using triamcinolone. Do not stop using triamcinolone suddenly, or you could have unpleasant withdrawal symptoms. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication. Carry an ID card or wear a medical alert bracelet stating that you are taking a steroid, in case of emergency. Any doctor, dentist, or emergency medical care provider who treats you should know that you are taking steroid medication. Store triamcinolone at room temperature away from moisture and heat. What happens if I miss a dose? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of triamcinolone is not expected to produce life threatening symptoms. However, long term use of high steroid doses can lead to symptoms such as thinning skin, easy bruising, changes in the shape or location of body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex. What should I avoid? Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chicken pox or measles. These conditions can be serious or even fatal in people who are using triamcinolone. Do not receive a "live" vaccine while using triamcinolone. The vaccine may not work as well during this time, and may not fully protect you from disease. Avoid drinking alcohol while you are taking triamcinolone. Triamcinolone side effects Get emergency medical help if you have any of these signs of an allergic reaction to triamcinolone: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as: problems with your vision; swelling, rapid weight gain, feeling short of breath; severe depression, unusual thoughts or behavior, seizure (convulsions); bloody or tarry stools, coughing up blood; pancreatitis (severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate); low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling); or dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure). Less serious triamcinolone side effects may include: sleep problems (insomnia), mood changes; acne, dry skin, thinning skin, bruising or discoloration; slow wound healing; increased sweating; headache, dizziness, spinning sensation; nausea, stomach pain, bloating; muscle weakness; or changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist); This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. What other drugs will affect triamcinolone? Many drugs can interact with triamcinolone. Below is just a partial list. Tell your doctor if you are using: aspirin (taken on a daily basis or at high doses); a diuretic (water pill); a blood thinner such as warfarin (Coumadin, Jantoven); cyclosporine (Gengraf, Neoral, Sandimmune); insulin or diabetes medications you take by mouth; ketoconazole (Nizoral); rifampin (Rifadin, Rifater, Rifamate, Rimactane); or seizure medications such as phenytoin (Dilantin) or phenobarbital (Luminal, Solfoton). This list is not complete and other drugs may interact with triamcinolone. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
What is triamcinolone? Triamcinolone belongs to a class of drugs called corticosteroids. It prevents the release of substances in the body that cause inflammation. Triamcinolone oral (taken by mouth) is used to treat many different conditions such as allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, or breathing disorders. Triamcinolone may also be used for purposes not listed in this medication guide. Warnings You should not use this medication if you are allergic to triamcinolone, or if you have a fungal infection anywhere in your body. Before taking triamcinolone, tell your doctor about all of your medical conditions, and about all other medicines you are using. There are many other disease that can be affected by steroid use, and many other medicines that can interact with steroids. Your steroid medication needs may change if you have any unusual stress such as a serious illness, fever or infection, or if you have surgery or a medical emergency. Tell your doctor about any such situation that affects you during treatment. Steroid medications such as triamcinolone can weaken your immune system, making it easier for you to get an infection or worsening an infection you already have or have recently had. Tell your doctor about any illness or infection you have had within the past several weeks. Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chicken pox or measles. These conditions can be serious or even fatal in people who are using steroid medication. Do not receive a "live" vaccine while you are taking triamcinolone. Vaccines may not work as well while you are taking a steroid. Do not stop using triamcinolone suddenly, or you could have unpleasant withdrawal symptoms. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication. Wear a medical alert tag or carry an ID card stating that you take triamcinolone. Any medical care provider who treats you should know that you take steroid medication. Before taking this medicine You should not use this medication if you are allergic to triamcinolone, or if you have a fungal infection anywhere in your body. Steroid medication can weaken your immune system, making it easier for you to get an infection. Steroids can also worsen an infection you already have, or reactivate an infection you recently had. Before taking this medication, tell your doctor about any illness or infection you have had within the past several weeks. To make sure you can safely take triamcinolone, tell your doctor if you have any of these other conditions: liver disease (such as cirrhosis); kidney disease; a thyroid disorder; diabetes; a history of malaria; tuberculosis; osteoporosis; a muscle disorder such as myasthenia gravis; glaucoma or cataracts; herpes infection of the eyes; stomach ulcers, ulcerative colitis, or diverticulitis; depression or mental illness; congestive heart failure; or high blood pressure FDA pregnancy category C. It is not known whether triamcinolone will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Triamcinolone can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Triamcinolone can affect growth in children. Talk with your doctor if you think your child is not growing at a normal rate while using triamcinolone. How should I take triamcinolone? Take triamcinolone exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results from this medication. Take triamcinolone with food to prevent stomach upset. Your steroid medication needs may change if you have unusual stress such as a serious illness, fever or infection, or if you have surgery or a medical emergency. Tell your doctor about any such situation that affects you. This medication can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you are using triamcinolone. Do not stop using triamcinolone suddenly, or you could have unpleasant withdrawal symptoms. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication. Carry an ID card or wear a medical alert bracelet stating that you are taking a steroid, in case of emergency. Any doctor, dentist, or emergency medical care provider who treats you should know that you are taking steroid medication. Store triamcinolone at room temperature away from moisture and heat. What happens if I miss a dose? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of triamcinolone is not expected to produce life threatening symptoms. However, long term use of high steroid doses can lead to symptoms such as thinning skin, easy bruising, changes in the shape or location of body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex. What should I avoid? Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chicken pox or measles. These conditions can be serious or even fatal in people who are using triamcinolone. Do not receive a "live" vaccine while using triamcinolone. The vaccine may not work as well during this time, and may not fully protect you from disease. Avoid drinking alcohol while you are taking triamcinolone. Triamcinolone side effects Get emergency medical help if you have any of these signs of an allergic reaction to triamcinolone: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as: problems with your vision; swelling, rapid weight gain, feeling short of breath; severe depression, unusual thoughts or behavior, seizure (convulsions); bloody or tarry stools, coughing up blood; pancreatitis (severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate); low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling); or dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure). Less serious triamcinolone side effects may include: sleep problems (insomnia), mood changes; acne, dry skin, thinning skin, bruising or discoloration; slow wound healing; increased sweating; headache, dizziness, spinning sensation; nausea, stomach pain, bloating; muscle weakness; or changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist); This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. What other drugs will affect triamcinolone? Many drugs can interact with triamcinolone. Below is just a partial list. Tell your doctor if you are using: aspirin (taken on a daily basis or at high doses); a diuretic (water pill); a blood thinner such as warfarin (Coumadin, Jantoven); cyclosporine (Gengraf, Neoral, Sandimmune); insulin or diabetes medications you take by mouth; ketoconazole (Nizoral); rifampin (Rifadin, Rifater, Rifamate, Rimactane); or seizure medications such as phenytoin (Dilantin) or phenobarbital (Luminal, Solfoton). This list is not complete and other drugs may interact with triamcinolone. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
What is hydrochlorothiazide and triamterene? Hydrochlorothiazide is a thiazide diuretic (water pill). Triamterene is a potassium-sparing diuretic. Hydrochlorothiazide and triamterene is a combination medicine that is used to treat fluid retention (edema) and high blood pressure (hypertension). hydrochlorothiazide and triamterene is usually given to people in whom other diuretics have caused hypokalemia (low potassium levels in your blood). Hydrochlorothiazide and triamterene may also be used for purposes not listed in this medication guide. Warnings You should not use this medicine if have kidney disease, urination problems, high levels of potassium in your blood, or if you are taking other diuretics similar to triamterene. This medicine can raise your blood potassium to dangerous levels, especially if you have kidney disease, diabetes, severe illness, or if you are an older adult. Call your doctor right away if you have signs of high potassium: nausea, tingly feeling, feeling weak or tired, slow heartbeats, or loss of movement. Before taking this medicine You should not use hydrochlorothiazide and triamterene if you are allergic to hydrochlorothiazide or triamterene, or if: you have kidney disease or are unable to urinate; you have high potassium levels (hyperkalemia); you are taking diuretics similar to triamterene, such as amiloride or spironolactone; or you are taking potassium supplements (unless your doctor tells you to). Diuretics such as triamterene can raise your blood potassium to dangerous levels. This is more likely to occur if you have kidney disease, diabetes, severe illness, or if you are an older adult. Ask your doctor about your individual risk. Tell your doctor if you have ever had: diabetes; cirrhosis or other liver disease; heart disease, heart rhythm disorder; gout; cataracts or glaucoma; an allergy to sulfa drugs or penicillin; kidney stones; o if you are on a low-salt diet. It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. You should not breastfeed while using this medicine. This medicine is not approved for use by anyone younger than 18 years old. How should I take hydrochlorothiazide and triamterene? Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Hydrochlorothiazide and triamterene is usually taken once per day. You may need frequent medical tests. Even if you have no symptoms, tests can help your doctor determine if this medicine is effective. Your heart function may also need to be checked using an electrocardiograph or ECG (sometimes called an EKG). Severe illness can affect your potassium levels. Call your doctor if you have a serious illness, injury, or medical emergency. If you need surgery or medical tests, tell the doctor you currently use this medicine. You may need to stop for a short time. If you have high blood pressure, keep using this medicine even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life. Store at room temperature away from moisture, heat, and light. What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include increased urination, nausea, vomiting, weakness, fever, warmth or flushing in your face, or muscle spasms. What should I avoid while taking hydrochlorothiazide and triamterene? Do not use potassium supplements, salt substitutes, or low-sodium milk unless your doctor has told you to. Avoid a diet high in salt. Too much salt will cause your body to retain water and can make hydrochlorothiazide and triamterene less effective. Hydrochlorothiazide may increase your risk of skin cancer. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Your doctor may want you to have skin examinations on a regular basis. Avoid becoming overheated or dehydrated during exercise, in hot weather, or by not drinking enough fluids. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough. Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired. Hydrochlorothiazide and triamterene side effects Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling). Stop taking this medicine and call your doctor at once if you have: blurred vision, tunnel vision, eye pain, or seeing halos around lights; a light-headed feeling, like you might pass out; fast, slow, or uneven heart rate; signs of liver or pancreas problems--loss of appetite, upper stomach pain (that may spread to your back), nausea or vomiting, fast heart rate, dark urine, jaundice (yellowing of the skin or eyes); high potassium level--nausea, weakness, tingly feeling, feeling weak or tired, slow heartbeats, loss of movement; low potassium level--leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling; kidney problems--little or no urination, swelling in your feet or ankles, feeling tired or short of breath; lupus-like symptoms--muscle or joint pain, flu symptoms, chest pain, and a rash or patchy skin color that worsens in sunlight; or other signs of an electrolyte imbalance--thirst, dry mouth, stomach pain, drowsiness, weakness, fast heart rate, muscle pain or weakness, feeling restless or light-headed. Common side effects may include: stomach pain, nausea, diarrhea, constipation; dizziness, headache; blurred vision; or dry mouth. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Hydrochlorothiazide / triamterene side effects (more detail) Hydrochlorothiazide and triamterene dosing information Usual Adult Dose for Edema: Hydrochlorothiazide 25 to 50 mg-Triamterene 37.5 to 100 mg orally once a day Comments: -Patients who become hypokalemic on 50 mg of hydrochlorothiazide may be transferred directly to hydrochlorothiazide 50 mg-triamterene 75 mg orally once a day. Patients who become hypokalemic on 25 mg of hydrochlorothiazide may be transferred directly to hydrochlorothiazide 25 mg-triamterene 37.5 mg orally once a day. -Patients in whom hypokalemia cannot be risked may be initiated on hydrochlorothiazide 25 mg-triamterene 37.5 mg orally once a day. Uses: -Treatment of hypertension or edema in patients who develop hypokalemia on hydrochlorothiazide alone. -Initial therapy of hypertension or edema for patients in whom hypokalemia cannot be risked (e.g., patients on concomitant digitalis preparations or with a history of cardiac arrhythmias, etc.). Usual Adult Dose for Hypertension: Hydrochlorothiazide 25 to 50 mg-Triamterene 37.5 to 100 mg orally once a day Comments: -Patients who become hypokalemic on 50 mg of hydrochlorothiazide may be transferred directly to hydrochlorothiazide 50 mg-triamterene 75 mg orally once a day. Patients who become hypokalemic on 25 mg of hydrochlorothiazide may be transferred directly to hydrochlorothiazide 25 mg-triamterene 37.5 mg orally once a day. -Patients in whom hypokalemia cannot be risked may be initiated on hydrochlorothiazide 25 mg-triamterene 37.5 mg orally once a day. Uses: -Treatment of hypertension or edema in patients who develop hypokalemia on hydrochlorothiazide alone. -Initial therapy of hypertension or edema for patients in whom hypokalemia cannot be risked (e.g., patients on concomitant digitalis preparations or with a history of cardiac arrhythmias, etc.). Detailed Hydrochlorothiazide / triamterene dosage information What other drugs can affect hydrochlorothiazide and triamterene? Tell your doctor about all your other medicines, especially: any other blood pressure medicine; amphotericin B; chlorpropamide; digoxin; laxatives; lithium; methenamine; a blood thinner; oral diabetes medicine; steroid medication (prednisone and others); an ACE inhibitor--benazepril, captopril, enalapril, fosinopril, lisinopril, moexipril, perindopril, quinapril, ramipril, trandolapril; or NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others. This list is not complete. Other drugs may affect hydrochlorothiazide and triamterene, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
What is hydrochlorothiazide and triamterene? Hydrochlorothiazide is a thiazide diuretic (water pill). Triamterene is a potassium-sparing diuretic. Hydrochlorothiazide and triamterene is a combination medicine that is used to treat fluid retention (edema) and high blood pressure (hypertension). hydrochlorothiazide and triamterene is usually given to people in whom other diuretics have caused hypokalemia (low potassium levels in your blood). Hydrochlorothiazide and triamterene may also be used for purposes not listed in this medication guide. Warnings You should not use this medicine if have kidney disease, urination problems, high levels of potassium in your blood, or if you are taking other diuretics similar to triamterene. This medicine can raise your blood potassium to dangerous levels, especially if you have kidney disease, diabetes, severe illness, or if you are an older adult. Call your doctor right away if you have signs of high potassium: nausea, tingly feeling, feeling weak or tired, slow heartbeats, or loss of movement. Before taking this medicine You should not use hydrochlorothiazide and triamterene if you are allergic to hydrochlorothiazide or triamterene, or if: you have kidney disease or are unable to urinate; you have high potassium levels (hyperkalemia); you are taking diuretics similar to triamterene, such as amiloride or spironolactone; or you are taking potassium supplements (unless your doctor tells you to). Diuretics such as triamterene can raise your blood potassium to dangerous levels. This is more likely to occur if you have kidney disease, diabetes, severe illness, or if you are an older adult. Ask your doctor about your individual risk. Tell your doctor if you have ever had: diabetes; cirrhosis or other liver disease; heart disease, heart rhythm disorder; gout; cataracts or glaucoma; an allergy to sulfa drugs or penicillin; kidney stones; o if you are on a low-salt diet. It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. You should not breastfeed while using this medicine. This medicine is not approved for use by anyone younger than 18 years old. How should I take hydrochlorothiazide and triamterene? Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Hydrochlorothiazide and triamterene is usually taken once per day. You may need frequent medical tests. Even if you have no symptoms, tests can help your doctor determine if this medicine is effective. Your heart function may also need to be checked using an electrocardiograph or ECG (sometimes called an EKG). Severe illness can affect your potassium levels. Call your doctor if you have a serious illness, injury, or medical emergency. If you need surgery or medical tests, tell the doctor you currently use this medicine. You may need to stop for a short time. If you have high blood pressure, keep using this medicine even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life. Store at room temperature away from moisture, heat, and light. What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include increased urination, nausea, vomiting, weakness, fever, warmth or flushing in your face, or muscle spasms. What should I avoid while taking hydrochlorothiazide and triamterene? Do not use potassium supplements, salt substitutes, or low-sodium milk unless your doctor has told you to. Avoid a diet high in salt. Too much salt will cause your body to retain water and can make hydrochlorothiazide and triamterene less effective. Hydrochlorothiazide may increase your risk of skin cancer. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Your doctor may want you to have skin examinations on a regular basis. Avoid becoming overheated or dehydrated during exercise, in hot weather, or by not drinking enough fluids. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough. Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired. Hydrochlorothiazide and triamterene side effects Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling). Stop taking this medicine and call your doctor at once if you have: blurred vision, tunnel vision, eye pain, or seeing halos around lights; a light-headed feeling, like you might pass out; fast, slow, or uneven heart rate; signs of liver or pancreas problems--loss of appetite, upper stomach pain (that may spread to your back), nausea or vomiting, fast heart rate, dark urine, jaundice (yellowing of the skin or eyes); high potassium level--nausea, weakness, tingly feeling, feeling weak or tired, slow heartbeats, loss of movement; low potassium level--leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling; kidney problems--little or no urination, swelling in your feet or ankles, feeling tired or short of breath; lupus-like symptoms--muscle or joint pain, flu symptoms, chest pain, and a rash or patchy skin color that worsens in sunlight; or other signs of an electrolyte imbalance--thirst, dry mouth, stomach pain, drowsiness, weakness, fast heart rate, muscle pain or weakness, feeling restless or light-headed. Common side effects may include: stomach pain, nausea, diarrhea, constipation; dizziness, headache; blurred vision; or dry mouth. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Hydrochlorothiazide / triamterene side effects (more detail) Hydrochlorothiazide and triamterene dosing information Usual Adult Dose for Edema: Hydrochlorothiazide 25 to 50 mg-Triamterene 37.5 to 100 mg orally once a day Comments: -Patients who become hypokalemic on 50 mg of hydrochlorothiazide may be transferred directly to hydrochlorothiazide 50 mg-triamterene 75 mg orally once a day. Patients who become hypokalemic on 25 mg of hydrochlorothiazide may be transferred directly to hydrochlorothiazide 25 mg-triamterene 37.5 mg orally once a day. -Patients in whom hypokalemia cannot be risked may be initiated on hydrochlorothiazide 25 mg-triamterene 37.5 mg orally once a day. Uses: -Treatment of hypertension or edema in patients who develop hypokalemia on hydrochlorothiazide alone. -Initial therapy of hypertension or edema for patients in whom hypokalemia cannot be risked (e.g., patients on concomitant digitalis preparations or with a history of cardiac arrhythmias, etc.). Usual Adult Dose for Hypertension: Hydrochlorothiazide 25 to 50 mg-Triamterene 37.5 to 100 mg orally once a day Comments: -Patients who become hypokalemic on 50 mg of hydrochlorothiazide may be transferred directly to hydrochlorothiazide 50 mg-triamterene 75 mg orally once a day. Patients who become hypokalemic on 25 mg of hydrochlorothiazide may be transferred directly to hydrochlorothiazide 25 mg-triamterene 37.5 mg orally once a day. -Patients in whom hypokalemia cannot be risked may be initiated on hydrochlorothiazide 25 mg-triamterene 37.5 mg orally once a day. Uses: -Treatment of hypertension or edema in patients who develop hypokalemia on hydrochlorothiazide alone. -Initial therapy of hypertension or edema for patients in whom hypokalemia cannot be risked (e.g., patients on concomitant digitalis preparations or with a history of cardiac arrhythmias, etc.). Detailed Hydrochlorothiazide / triamterene dosage information What other drugs can affect hydrochlorothiazide and triamterene? Tell your doctor about all your other medicines, especially: any other blood pressure medicine; amphotericin B; chlorpropamide; digoxin; laxatives; lithium; methenamine; a blood thinner; oral diabetes medicine; steroid medication (prednisone and others); an ACE inhibitor--benazepril, captopril, enalapril, fosinopril, lisinopril, moexipril, perindopril, quinapril, ramipril, trandolapril; or NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others. This list is not complete. Other drugs may affect hydrochlorothiazide and triamterene, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
What is trospium? Trospium relieves spasms of the bladder. Trospium is used to treat overactive bladder and symptoms of urinary incontinence, frequency, and urgency. Trospium may also be used for purposes not listed in this medication guide. Warnings You should not take trospium if you are allergic to trospium, or if you have untreated or uncontrolled narrow-angle glaucoma, a blockage in your digestive system, or if you are unable to urinate. Take trospium on an empty stomach, at least 1 hour before a meal. Avoid drinking alcohol within 2 hours before or after you take trospium. Drinking alcohol can increase certain side effects of trospium. This medication may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly. Avoid becoming overheated or dehydrated during exercise and in hot weather. Trospium can decrease sweating, which makes it easier for you to have heat stroke. Drink plenty of fluids while you are taking this medication. Before using trospium, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by trospium. Before taking this medicine You should not use trospium if you are allergic to it, or if you have: untreated or uncontrolled narrow-angle glaucoma; a blockage in your digestive system; or if you are unable to urinate. To make sure you can safely take trospium, tell your doctor if you have any of these other conditions: glaucoma; liver disease; kidney disease; a stomach or intestinal disorder such as ulcerative colitis; a muscle disorder such as myasthenia gravis; or an enlarged prostate. FDA pregnancy category C. It is not known whether trospium will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether trospium passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Older adults may be more likely to have side effects from this medicine. How should I take trospium? Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Take trospium on an empty stomach, at least 1 hour before a meal. Extended-release trospium (Sanctura XR) should be taken once each morning, at least 1 hour before a meal. Do not crush, chew, break, or open an extended-release capsule. Swallow it whole. Breaking or opening the pill may cause too much of the drug to be released at one time. Store at room temperature away from moisture and heat. What happens if I miss a dose? Take the missed dose 1 hour before your next meal. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include severe forms of some of the side effects listed in this medication guide. What should I avoid while taking trospium? This medication may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly. Avoid drinking alcohol within 2 hours before or after you take trospium. Drinking alcohol can increase certain side effects of trospium. Avoid becoming overheated or dehydrated during exercise and in hot weather. Trospium can decrease sweating, which makes it easier for you to have heat stroke. Drink plenty of fluids while you are taking this medication. Trospium side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using trospium and call your doctor at once if you have a serious side effect such as: severe stomach pain or bloating; severe constipation; urinating less than usual or not at all; or confusion, hallucinations. Less serious side effects may include: dry mouth or throat; headache; mild constipation; upset stomach, gas; dizziness, drowsiness, or dry eyes. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Trospium dosing information Usual Adult Dose for Urinary Incontinence: Immediate-release formulation: 20 mg orally 2 times a day Extended-release formulation: 60 mg orally once a day in the morning Use: for overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency Usual Adult Dose for Urinary Frequency: Immediate-release formulation: 20 mg orally 2 times a day Extended-release formulation: 60 mg orally once a day in the morning Use: for overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency Usual Geriatric Dose for Urinary Incontinence: Immediate-release formulation: 75 years and older: 20 mg orally once a day based on tolerability Extended-release formulation: 60 mg orally once a day in the morning Use: for overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency Usual Geriatric Dose for Urinary Frequency: Immediate-release formulation: 75 years and older: 20 mg orally once a day based on tolerability Extended-release formulation: 60 mg orally once a day in the morning Use: for overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency What other drugs will affect trospium? Before using trospium, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by trospium. Tell your doctor about all other medicines you use, especially: atropine (Atreza, Sal-Tropine, and others); belladonna (Donnatal, and others); benztropine (Cogentin); dimenhydrinate (Dramamine); metformin (Actoplus Met, Avandamet, Glucophage, Glucovance, Janumet, Kombiglyze, Metaglip, PrandiMet); morphine (Kadian, MS Contin, Oramorph); procainamide (Procanbid, Pronestyl); tenofovir (Viread); vancomycin (Vancocin); bronchodilators such as ipratropium (Atrovent) or tiotropium (Spiriva); bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare); irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Hyomax), or propantheline (Pro Banthine); or ulcer medications such as glycopyrrolate (Robinul) or mepenzolate (Cantil). This list is not complete and other drugs may interact with trospium. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
What is Uroxatral? Uroxatral (alfuzosin) is an alpha-adrenergic (AL-fa ad-ren-ER-Jk) blocker. Uroxatral helps relax the muscles in the prostate and bladder neck, making it easier to urinate. Uroxatral is used to improve urination in men with benign prostatic hyperplasia (enlarged prostate). Warnings You should not take Uroxatral if you have moderate to severe liver disease. Many drugs can affect alfuzosin, and some should not be used at the same time. Tell your doctor about all your current medicines and any you start or stop using. Uroxatral lowers blood pressure and may cause dizziness or fainting, especially if you take heart or blood pressure medications. Avoid driving or hazardous activity until you know how alfuzosin will affect you. Call your doctor at once if you have a light-headed feeling, like you might pass out. Uroxatral can affect your pupils during cataract surgery. Tell your eye surgeon ahead of time that you are using this medication. Do not stop using this medicine before surgery unless your surgeon tells you to. There are many other drugs that can interact with alfuzosin. Tell your doctor about all medications you use. Before taking this medicine You should not take Uroxatral if you are allergic to alfuzosin, or if you have: moderate to severe liver disease. Some medicines can cause unwanted or dangerous effects when used with Uroxatral. Your doctor may change your treatment plan if you also use: an antibiotic; antifungal medicine; heart medication; antiviral medicine to treat hepatitis C or HIV/AIDS; or medicines similar to alfuzosin (doxazosin, prazosin, silodosin, tamsulosin, or terazosin). Tell your doctor if you have ever had: low blood pressure, especially if caused by taking medications; liver disease; kidney disease; prostate cancer; or long QT syndrome (in you or a family member). Uroxatral can affect your pupils. If you have cataract surgery, tell your surgeon ahead of time that you use this medicine. Alfuzosin is not for use in women, and the effects of this medicine during pregnancy or in breastfeeding women are unknown. Uroxatral is not approved for use by anyone younger than 18 years old. How should I take Uroxatral? Take Uroxatral exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Your doctor may test your prostate specific antigen (PSA) to check for prostate cancer before you take this medicine. Uroxatral is usually taken once daily just after a meal, at the same time each day. Do not take the medicine on an empty stomach. Swallow the tablet whole and do not crush, chew, or break it. Alfuzosin lowers blood pressure and may cause dizziness or fainting, especially when you first start taking it. You may feel very dizzy when you first wake up. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Your blood pressure will need to be checked often. Some things can cause your blood pressure to get too low. This includes vomiting, diarrhea, or heavy sweating. Call your doctor if you are sick with vomiting or diarrhea. Store at room temperature away from moisture, heat, and light. Dosing information Usual Adult Dose for Benign Prostatic Hyperplasia: Extended-release tablet: 10 mg orally once a day immediately after the same meal each day What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What to avoid Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired. Drinking alcohol with this medicine can cause side effects. Uroxatral side effects Get emergency medical help if you have signs of an allergic reaction to Uroxatral: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: a light-headed feeling, like you might pass out; new or worsening chest pain; upper stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or penis erection that is painful or lasts 4 hours or longer. Common Uroxatral side effects may include: dizziness; headache; or feeling tired. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. What other drugs will affect Uroxatral? Tell your doctor about all your current medicines. Many drugs can increase your risk of very low blood pressure while taking Uroxatral, especially: heart or blood pressure medication; nitrate medication (such as nitroglycerin); or sildenafil (Viagra) and other erectile dysfunction medicines. This list is not complete. Many other drugs can interact with alfuzosin, and some drugs should not be used at the same time. Tell your doctor about all your current medicines and any medicine you start or stop using. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.
What is ursodiol? Ursodiol capsules are used to dissolve small gallstones that cannot be removed with surgery, or to prevent gallstones that may occur during rapid weight loss. Ursodiol will not dissolve calcified gallstones. Ursodiol tablets are used to treat primary biliary cirrhosis, an autoimmune disorder that causes progressive destruction of the bile ducts in your liver. Ursodiol may also be used for purposes not listed in this medication guide. Warnings Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies. Before taking this medicine You should not use ursodiol if you are allergic to it, or if you have an obstruction in your liver or gallbladder. Tell your doctor if: you have been coughing up blood; or you have gained weight rapidly, especially in your face and midsection. Tell your doctor if you are pregnant or breastfeeding. Not approved for use by anyone younger than 18 years old. How should I take ursodiol? Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Take the ursodiol tablet with food. You may need to break a tablet in half to get your correct dose. Swallow each tablet piece whole with a glass of water. A broken tablet may have a bitter taste. After breaking a tablet, keep it separate from the whole tablets and use it within 28 days after breaking. Use ursodiol regularly for the best results. Doses are based on weight. Your dose may change if you gain or lose weight. You may need medical tests, including gallbladder ultrasound exams and blood tests to check your liver function. You may also need liver function tests every 6 months after you stop using ursodiol. Call your doctor if your symptoms do not improve, or if they get worse. To treat gallstones, you may have to take ursodiol for several months. Some gallstones may not completely dissolve, and you may develop new gallstones within 5 years after treatment. Ask your doctor about your risk. Store tightly closed at room temperature, away from moisture and heat. What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. Get your prescription refilled before you run out of medicine completely. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking ursodiol? Ask your doctor before taking an antacid, and take only the type your doctor recommends. Ursodiol side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: pain or burning when you urinate; liver problems--nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or signs of a new infection--sudden weakness or ill feeling, fever, chills, sore throat, mouth sores, skin sores, trouble swallowing. Common side effects may include: upset stomach, nausea, vomiting; diarrhea, constipation; cough, sore throat; painful urination; hair loss; or back pain. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Ursodiol dosing information Usual Adult Dose for Biliary Cirrhosis: Tablets: 13 to 15 mg/kg orally per day, given in 2 to 4 divided doses with food Comments: -The dose should be adjusted to the patient's needs. -Scored tablets may be broken in half to provide recommended doses. Use: Treatment of patients with primary biliary cirrhosis (PBC) Usual Adult Dose for Gallbladder Disease: Capsules: Gallstone dissolution: 8 to 10 mg/kg orally per day, given in 2 to 3 divided doses Gallstone prevention: 300 mg orally 2 times a day -Maximum dose: 600 mg/day Comments: -Safety in the dissolution of gallstones has not been established in patients using this drug beyond 24 months. -Ultrasound images should be obtained every 6 months for the first year. -If gallstones appear to have dissolved, treatment should be continued, and dissolution should be confirmed on a repeat ultrasound in 1 to 3 months. -Most patients who achieve complete dissolution show partial or complete dissolution at the first on-treatment reevaluation. -If partial stone dissolution is not observed after 12 months of treatment, the likelihood of treatment is significantly reduced. Uses: -Patients with radiolucent, noncalcified gallbladder stones less than 20 mm in greatest diameter in whom elective cholecystectomy would be undertaken except for the presence of increased surgical risk due to advanced age, idiosyncratic reaction to general anesthesia, systemic disease, or those who refuse surgery -For the prevention of gallstone formation in obese patients experiencing rapid weight loss What other drugs will affect ursodiol? It may be harder for your body to absorb ursodiol if you take certain cholesterol-lowering medicines, such as: cholestyramine; or colestipol. Tell your doctor about all your other medicines, especially birth control pills and other estrogens. Other drugs may affect ursodiol, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
What is ursodiol? Ursodiol capsules are used to dissolve small gallstones that cannot be removed with surgery, or to prevent gallstones that may occur during rapid weight loss. Ursodiol will not dissolve calcified gallstones. Ursodiol tablets are used to treat primary biliary cirrhosis, an autoimmune disorder that causes progressive destruction of the bile ducts in your liver. Ursodiol may also be used for purposes not listed in this medication guide. Warnings Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies. Before taking this medicine You should not use ursodiol if you are allergic to it, or if you have an obstruction in your liver or gallbladder. Tell your doctor if: you have been coughing up blood; or you have gained weight rapidly, especially in your face and midsection. Tell your doctor if you are pregnant or breastfeeding. Not approved for use by anyone younger than 18 years old. How should I take ursodiol? Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Take the ursodiol tablet with food. You may need to break a tablet in half to get your correct dose. Swallow each tablet piece whole with a glass of water. A broken tablet may have a bitter taste. After breaking a tablet, keep it separate from the whole tablets and use it within 28 days after breaking. Use ursodiol regularly for the best results. Doses are based on weight. Your dose may change if you gain or lose weight. You may need medical tests, including gallbladder ultrasound exams and blood tests to check your liver function. You may also need liver function tests every 6 months after you stop using ursodiol. Call your doctor if your symptoms do not improve, or if they get worse. To treat gallstones, you may have to take ursodiol for several months. Some gallstones may not completely dissolve, and you may develop new gallstones within 5 years after treatment. Ask your doctor about your risk. Store tightly closed at room temperature, away from moisture and heat. What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. Get your prescription refilled before you run out of medicine completely. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking ursodiol? Ask your doctor before taking an antacid, and take only the type your doctor recommends. Ursodiol side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: pain or burning when you urinate; liver problems--nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or signs of a new infection--sudden weakness or ill feeling, fever, chills, sore throat, mouth sores, skin sores, trouble swallowing. Common side effects may include: upset stomach, nausea, vomiting; diarrhea, constipation; cough, sore throat; painful urination; hair loss; or back pain. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Ursodiol dosing information Usual Adult Dose for Biliary Cirrhosis: Tablets: 13 to 15 mg/kg orally per day, given in 2 to 4 divided doses with food Comments: -The dose should be adjusted to the patient's needs. -Scored tablets may be broken in half to provide recommended doses. Use: Treatment of patients with primary biliary cirrhosis (PBC) Usual Adult Dose for Gallbladder Disease: Capsules: Gallstone dissolution: 8 to 10 mg/kg orally per day, given in 2 to 3 divided doses Gallstone prevention: 300 mg orally 2 times a day -Maximum dose: 600 mg/day Comments: -Safety in the dissolution of gallstones has not been established in patients using this drug beyond 24 months. -Ultrasound images should be obtained every 6 months for the first year. -If gallstones appear to have dissolved, treatment should be continued, and dissolution should be confirmed on a repeat ultrasound in 1 to 3 months. -Most patients who achieve complete dissolution show partial or complete dissolution at the first on-treatment reevaluation. -If partial stone dissolution is not observed after 12 months of treatment, the likelihood of treatment is significantly reduced. Uses: -Patients with radiolucent, noncalcified gallbladder stones less than 20 mm in greatest diameter in whom elective cholecystectomy would be undertaken except for the presence of increased surgical risk due to advanced age, idiosyncratic reaction to general anesthesia, systemic disease, or those who refuse surgery -For the prevention of gallstone formation in obese patients experiencing rapid weight loss What other drugs will affect ursodiol? It may be harder for your body to absorb ursodiol if you take certain cholesterol-lowering medicines, such as: cholestyramine; or colestipol. Tell your doctor about all your other medicines, especially birth control pills and other estrogens. Other drugs may affect ursodiol, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
What is valacyclovir? slows the growth and spread of the herpes virus to help the body fight the infection. Valacyclovir is used to treat infections caused by herpes viruses, including genital herpes, cold sores, and shingles (herpes zoster) in adults. Valacyclovir is used to treat cold sores in children who are at least 12 years old, or chickenpox in children who are at least 2 years old. Valacyclovir will not cure herpes and will not prevent you from spreading the virus to other people. However, this medicine can lessen the symptoms of an infection. Warnings Before taking valacyclovir, tell your doctor if you have HIV/AIDS, a weak immune system, kidney disease (or if you are on dialysis), or if you have had a kidney or bone marrow transplant. Valacyclovir can be harmful to the kidneys, and these effects are increased when it is used together with other medicines that can harm the kidneys. Tell your doctor about all other medications you are using. You may need dose adjustments or special tests when taking certain medications together with valacyclovir. Treatment with valacyclovir should be started as soon as possible after the first appearance of symptoms (such as tingling, burning, blisters). Valacyclovir will not prevent the spread of genital herpes. Herpes infections are contagious and you can infect other people even while you are taking this medicine. Stop taking valacyclovir and call your doctor right away if you have any signs of a serious side effect that can harm red blood cells, such as: fever, easy bruising or bleeding, red spots on the skin (not related to herpes or chickenpox), bloody diarrhea, vomiting, pale or yellowed skin, weakness, fainting, or urinating less than usual or not at all. Before taking this medicine You should not use this medicine if you are allergic to valacyclovir or acyclovir (Zovirax). To make sure valacyclovir is safe for you, tell your doctor if you have: kidney disease (or if you are on dialysis); HIV/AIDS, or other conditions that can weaken the immune system; or a history of kidney transplant or bone marrow transplant. It is not known whether this medicine will harm an unborn baby. However, herpes virus can be passed from an infected mother to her baby during childbirth. If you have genital herpes, it is very important to prevent herpes lesions during your pregnancy, so that you do not have a genital lesion when your baby is born. Valacyclovir can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby. Do not give valacyclovir to a child without medical advice. How should I take valacyclovir? Take valacyclovir exactly as it was prescribed for you. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. Start taking valacyclovir as soon as possible after the first appearance of symptoms (such as tingling, burning, blisters). This medicine might not be as effective if you first start taking it 1 or 2 days after the start of your symptoms. Some herpes infections need to be treated for longer than others. Use this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may increase the risk of your virus becoming resistant to antiviral medicine. You may take valacyclovir with or without food. Tell your doctor if a child taking this medicine cannot swallow the valacyclovir tablet. Drink plenty of water while you are taking valacyclovir to keep your kidneys working properly. Lesions caused by herpes viruses should be kept as clean and dry as possible. Wearing loose clothing may help to prevent irritation of the lesions. Store valacyclovir tablets at room temperature away from moisture and heat. What happens if I miss a dose? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What to avoid Taking this medicine will not prevent you from passing genital herpes to other people. Herpes infections are contagious and you can infect other people even while you are taking with valacyclovir. Avoid sexual intercourse or use a latex condom to help keep you from spreading the virus to others. Avoid letting infected areas come into contact with other people. Avoid touching an infected area and then touching your eyes. Wash your hands frequently to prevent the spread of infection. Do not share valacyclovir with another person, even if they have the same symptoms you have. Valacyclovir side effects Get emergency medical help if you have signs of an allergic reaction to valacyclovir: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: confusion, aggression, or you feel shaky or unsteady; hallucinations (seeing or hearing things that are not real); problems with speech; a seizure (convulsions); or kidney problems--little or no urination, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath. Stop taking valacyclovir and call your doctor right away if you have any of the following signs of a serious side effect that can harm red blood cells: fever, pale skin; unusual bleeding (nosebleeds, bleeding gums); red or pink urine, little or no urination; red spots on the skin (not related to herpes or chickenpox); feeling weak or tired; stomach pain, bloody diarrhea, vomiting; or swelling in your face, hands, or feet. Side effects may be more likely in adults who are 65 or older. Common valacyclovir side effects may include: nausea, stomach pain; or headache. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. What other drugs will affect valacyclovir? Valacyclovir can harm your kidneys. This effect is increased when you also use certain other medicines, including: antivirals, chemotherapy, injected antibiotics, medicine for bowel disorders, medicine for high blood pressure, medicine to prevent organ transplant rejection, injectable osteoporosis medication, and some pain or arthritis medicines (including Advil, Motrin, and Aleve). Other drugs may interact with valacyclovir, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.